News tagged with wnt pathway
Ancient gene gives planarians a heads-up in regeneration
A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow ...
May 12, 2011 |
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Gut microbes promote cell turnover by a well-known pathway
Microbes matter -- perhaps more than anyone realizes -- in basic biological development and, maybe, they could be a target for reducing cancer risks, according to University of Oregon researchers.
Medicine & Health / Medical research
Oct 07, 2010 |
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Scientists show Six3 gene essential for retinal development
New research led by St. Jude Children's Research Hospital investigators adds to evidence that the Six3 gene functions like a doorman in the developing brain and visual system, safeguarding the future retina by keeping the ...
Sep 20, 2010 |
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New insight into 'accelerated aging' disease
Hutchinson-Gilford Progeria Syndrome (HGPS or progeria) is a rare genetic disease that causes young children to develop symptoms associated with advanced age, such as baldness, wrinkles, osteoporosis and cardiovascular disease. ...
Medicine & Health / Medical research
Sep 13, 2010 |
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Exosomal release of beta-catenin may explain why CD82 and CD9 suppress tumor metastasis
Researchers reveal a new way in which cells restrain beta-catenin and potentially suppress tumor metastasis: the protein can be ejected from cells in small vesicles called exosomes. The study appears online ...
Sep 13, 2010 |
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Tumor suppressor APC could stop cancer through its effect on actin cytoskeleton
The APC protein serves as the colon's guardian, keeping tumors at bay. Now researchers reveal a new function for the protein: helping to renovate the cytoskeleton by triggering actin assembly. The result suggests ...
Jun 21, 2010 |
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Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
Nov 25, 2009 |
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'Cross-talk' mechanism contributes to colorectal cancer
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
Nov 13, 2009 |
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Tapeworm Drug May Hold Promise For Colon Cancer, Future Research
(PhysOrg.com) -- Duke University Medical Center researchers have discovered an already-FDA-approved compound that can effectively “silence” a cell receptor shown to interfere with chemotherapy.
Nov 04, 2009 |
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Figuring out the heads or tails decision in regeneration
Amputations trigger a molecular response that determines if a head or tail will be regrown in planaria, a flatworm commonly studied for its regenerative capabilities. Until now, no molecular connection between wounding and ...
Medicine & Health / Medical research
Sep 14, 2009 |
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How to make a lung: Cell-regeneration molecules essential signals for early lung development
A tissue-repair-and-regeneration pathway in the human body, including wound healing, is essential for the early lung to develop properly. Genetically engineered mice fail to develop lungs when two molecules ...
Aug 17, 2009 |
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Targeting breast cancer stem cells in mice
Cancer develops when cells known as cancer stem cells begin to divide in an uncontrolled manner. Researchers from the University of Michigan Comprehensive Cancer Center have identified roles for the gene PTEN, ...
Jun 02, 2009 |
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