Mapping the 3-D geometry of SARS-CoV-2's genome

The novel coronavirus uses structures within its RNA to infect cells. Scientists have now identified these configurations, generating the most comprehensive atlas to date of SARS-CoV-2's genome.

MetaviralSPAdes—New assembler for virus genomes

When a new virus emerges, biologists rush to reconstruct its genome—a prerequisite for future diagnostic and vaccine development. The challenge with viral sequencing during an outbreak is that a sample from a patient, like ...

New study shines light on mysterious giant viruses

In recent years, giant viruses have been unearthed in several of the world's most mysterious locations, from the thawing permafrost of Siberia to locations unknown beneath the Antarctic ice. But don't worry, "The Thing" is ...

Mutations in SARS-CoV-2 offer insights into virus evolution

By analysing virus genomes from over 7,500 people infected with Covid-19, a UCL-led research team has characterised patterns of diversity of SARS-CoV-2 virus genome, offering clues to direct drugs and vaccine targets.

How do viruses mutate and jump species?

Viruses are little more than parasitic fragments of RNA or DNA. Despite this, they are astonishingly abundant in number and genetic diversity. We don't know how many virus species there are, but there could be trillions.

New coronavirus (SARS-CoV-2) mapped out

Jean and Peter Medawar wrote in 1977 that a virus is "simply a piece of bad news wrapped up in proteins." The 'bad news' in the SARS-CoV-2 case is the new coronavirus carries its mysterious genome in the form of a very long ...

First SARS-CoV-2 genomes in Austria openly available

The COVID-19 outbreak caused by the coronavirus SARS-CoV-2 was declared a pandemic by the World Health Organization (WHO) on 12 March 2020. It is thought to have been transmitted from wild animals to humans in the Chinese ...

Genome variation gives insight into coronavirus spread

As SARS-CoV-2 has spread around the world, its transmission rate has varied alongside variations in its genome, according to researchers at the University of California, Davis. Surveillance of the virus genome may help public ...

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