Compact CRISPR systems found in some of world's smallest microbes

UC Berkeley scientists have discovered simple CRISPR systems similar to CRISPR-Cas9—a gene-editing tool that has revolutionized biology—in previously unexplored bacteria that have eluded efforts to grow them in the laboratory.

SARS-CoV-2: Achilles' heel of viral RNA

When SARS-CoV-2 infects a cell, it introduces its RNA into it and re-programs it in such a way that the cell first produces viral proteins and then whole viral particles. In the search for active substances against SARS-CoV-2, ...

Coronavirus formation is successfully modeled

A physicist at the University of California, Riverside, and her former graduate student have successfully modeled the formation of SARS-CoV-2, the virus that spreads COVID-19, for the first time.

A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

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