News tagged with tumor suppressor
Researchers unravel biochemical factor important in tumor metastasis
A protein called "fascin" appears to play a critical transformation role in TGF beta mediated tumor metastasis, say researchers at Moffitt Cancer Center in Tampa, Fla., who published a study in a recent issue of the Journal of ...
Nov 09, 2011 |
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Microbiologists identify two molecules that kill lymphoma cells in mice
Researchers at the University of Southern California have identified two molecules that may be more effective cancer killers than are currently available on the market.
Nov 06, 2011 |
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Researchers identify potential molecular target to prevent growth of cancer cells
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Sep 16, 2011 |
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A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011 |
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Novel compound selectively kills cancer cells
A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing ...
Jul 13, 2011 |
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Computer modeling used to study protein involved with cancer, aging and chronic disease
(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...
Apr 13, 2011 |
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Researchers develop a screen for identifying new anticancer drug targets
Tumor suppressor genes normally control the growth of cells, but cancer can spring up when these genes are silenced by certain chemical reactions that modify chromosomes. Among the most common culprits responsible for inactivating ...
Apr 05, 2011 |
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Scientists report interplay between cancer and aging in mice
Cancer risk increases with age, and scientists have long perceived a possible evolutionary tradeoff between longer lifespan and greater risk of cancer. Now, researchers at Fox Chase Cancer Center find direct evidence for ...
Apr 05, 2011 |
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Researchers find link between DNA damage and immune response
Researchers offer the first evidence that DNA damage can lead to the regulation of inflammatory responses, the body's reaction to injury. The proteins involved in the regulation help protect the body from infection.
Mar 31, 2011 |
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New clue to controlling skin regeneration--as well as skin cancer
(PhysOrg.com) -- How do organs "know" when to stop growing? The answer could be useful in regenerative medicine, and also in cancer - where these "stop growing" signals either aren't issued or aren't heeded. Researchers in ...
Medicine & Health / Medical research
Mar 09, 2011 |
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Two proteins play key roles in Burkitt's lymphoma
Burkitt's lymphoma is one of the most aggressive tumors affecting humans. Multiple alterations in genes that regulate cell proliferation rate explain its aggressive behavior.
Mar 07, 2011 |
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Researchers find new role for cancer protein p53
The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are ...
Mar 02, 2011 |
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Eggs' quality control mechanism explained
To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...
Feb 17, 2011 |
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Researchers provide genetic evidence that antioxidants can help treat cancer
Researchers from Jefferson's Kimmel Cancer Center have genetic evidence suggesting the antioxidant drugs currently used to treat lung disease, malaria and even the common cold can also help prevent and treat cancers because ...
Feb 15, 2011 |
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Destined for disease: Breast cancer mutation regulates cell fate
A new study sheds light on why individuals who inherit a particular family of mutations have a high risk of developing a very aggressive form of breast cancer. The research, published by Cell Press on February 4th in the ...
Feb 03, 2011 |
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Tumor suppressor gene
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
For more information about Tumor suppressor gene, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
