News tagged with tumor suppressor protein
Related topics: cancer
Microbiologists identify two molecules that kill lymphoma cells in mice
Researchers at the University of Southern California have identified two molecules that may be more effective cancer killers than are currently available on the market.
Nov 06, 2011 |
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Researchers identify potential molecular target to prevent growth of cancer cells
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Sep 16, 2011 |
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A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011 |
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Computer modeling used to study protein involved with cancer, aging and chronic disease
(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...
Apr 13, 2011 |
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Scientists report interplay between cancer and aging in mice
Cancer risk increases with age, and scientists have long perceived a possible evolutionary tradeoff between longer lifespan and greater risk of cancer. Now, researchers at Fox Chase Cancer Center find direct evidence for ...
Apr 05, 2011 |
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Eggs' quality control mechanism explained
To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...
Feb 17, 2011 |
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Researchers provide genetic evidence that antioxidants can help treat cancer
Researchers from Jefferson's Kimmel Cancer Center have genetic evidence suggesting the antioxidant drugs currently used to treat lung disease, malaria and even the common cold can also help prevent and treat cancers because ...
Feb 15, 2011 |
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Scientists now know why some cancers become malignant and others don't
Cancer cells reproduce by dividing in two, but a molecule known as PML limits how many times this can happen, according to researchers lead by Dr. Gerardo Ferbeyre of the University of Montreal's Department of Biochemistry. ...
Jan 06, 2011 |
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Small molecule may disarm enemy of cancer-fighting p53
A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.
Dec 07, 2010 |
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Researchers link protein to tumor growth
(PhysOrg.com) -- Johns Hopkins researchers working on mice have discovered a protein that is a major target of a gene that, when mutated in humans, causes tumors to develop on nerves associated with hearing, as well as cataracts ...
Aug 31, 2010 |
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Use the common cold virus to target and disrupt cancer cells?
A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted ...
Aug 25, 2010 |
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Cancer-causing bacterium targets tumor-suppressor protein
Researchers have discovered a mechanism by which Helicobacter pylori, the only known cancer-causing bacterium, disables a tumor suppressor protein in host cells.
Aug 02, 2010 |
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Identification of a novel tumor suppressor
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI), have identified a novel tumor suppressor playing an important role in T-cell lymphoma. The protein kinase NDR1 ...
Jun 21, 2010 |
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Eliminating tumor suppressor C/EBP alpha explains cancer in aging liver
Understanding how the tumor suppressor protein C/EBP alpha is eliminated in aging livers gives important clues to the mechanism by which cancer occurs in that organ and could point the way to new therapies and prevention, ...
Jun 01, 2010 |
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MiRNA-21 linked to tumor suppressor loss, herceptin resistance
Overexpression of a specific type of microRNA can derail treatment by disabling an important molecular brake on breast cancer cell proliferation, according to evidence presented by researchers from The University of Texas ...
Apr 19, 2010 |
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