A research team led by Prof. Zhao Guoping from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has proposed a mechanism by which protein disulfide isomerase (PDI) can translocate ...
Cell & Microbiology
Oct 17, 2022
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6
The enzyme HDAC10 is involved in a variety of cellular processes associated with the development of a number of diseases. However, it is often not known exactly what role HDAC10 plays in the disease process. Scientists from ...
Biochemistry
Oct 12, 2022
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28
Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible. In the journal Angewandte Chemie, a research team has now described how a very low dose ...
Biochemistry
Oct 12, 2022
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44
Cancer is the second leading cause of death in Switzerland. Among the different types of cancers, non-small cell lung cancer (NSCLC) kills the most patients and remains largely incurable. Unfortunately, even newly approved ...
Cell & Microbiology
Oct 6, 2022
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68
Stanford University researchers have discovered a rapid and sustainable way to synthetically produce a promising cancer-fighting compound right in the lab. The compound's availability has been limited because its only currently ...
Biochemistry
Oct 3, 2022
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128
One approach to treating cancer is photodynamic therapy using photo-uncaging systems, in which light is used to activate a cancer-fighting agent in situ at the tumor. However, suitable agents must be stable under visible ...
Biochemistry
Sep 20, 2022
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104
Over the past 30 years, progress in early detection and treatment of cancer has helped reduce the overall death rate by more than 30%. Pancreatic cancer, however, has remained difficult to treat. Only 1 in 9 people survive ...
Bio & Medicine
Sep 13, 2022
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199
A team led by University of Minnesota Twin Cities biomedical engineers has developed a universally accessible application that can simulate complex molecular interactions, which will allow researchers to design better treatments ...
Biotechnology
Sep 6, 2022
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94
Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, ...
Cell & Microbiology
Sep 1, 2022
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59
Researchers have shown that a protein called fascin acts in the control center of cancer cells and influences their ability to repair themselves, grow and move, according to a study published today in eLife.
Cell & Microbiology
Aug 30, 2022
0
49
