When cancer spreads to the brain, treatment options fall off. Most of the drugs designed to target metastases do not cross the blood-brain barrier or are ineffective at treating brain metastases.
Bio & Medicine
Mar 31, 2023
0
61
White blood cells called neutrophils have an unappreciated role in eradicating solid tumors, according to a surprise discovery from a team led by Weill Cornell Medicine scientists.
Cell & Microbiology
Mar 30, 2023
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1
M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for their bactericidal and tumoricidal ...
Biochemistry
Mar 28, 2023
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52
In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system. By using computer-aided molecular design and machine learning, a Chinese research team has now developed ...
Biochemistry
Mar 27, 2023
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10
A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.
Bio & Medicine
Mar 16, 2023
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79
In order to deliver cancer therapeutics to tumor cells, the cells' membranes must be overcome. A team of researchers have discovered a simple way to achieve this using lipid nanoparticles containing the reagent EDTA (ethylenediaminetetraacetic ...
Bio & Medicine
Mar 16, 2023
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48
Macrophages are highly specialized cells of the immune system that help the body detect and fight deadly pathogens. In particular, M1-like macrophages detect and destroy tumor cells, and release protective chemokines such ...
Bio & Medicine
Mar 7, 2023
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20
Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer. Few drugs have proved effective at combating this uncontrolled growth of glial cells, which ...
Biochemistry
Mar 6, 2023
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57
Mount Sinai Health System and Memorial Sloan Kettering Cancer Center researchers have developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anti-cancer drugs to treat ...
Bio & Medicine
Mar 2, 2023
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77
Prof. Wang Hui, together with Prof. Lin Wenchu and associate Prof. Qian Junchao from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences, have recently reported a near infrared (NIR)-II-responsive ...
Bio & Medicine
Feb 17, 2023
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23
