News tagged with tumor cell migration

Researchers unravel biochemical factor important in tumor metastasis

A protein called "fascin" appears to play a critical transformation role in TGF beta mediated tumor metastasis, say researchers at Moffitt Cancer Center in Tampa, Fla., who published a study in a recent issue of the Journal of ...

Chemistry / Biochemistry

created Nov 09, 2011 | popularity not rated yet | comments 0

Newly discovered mechanism controls levels and efficacy of a marijuana-like substance in the brain

A newly discovered molecular mechanism helps control the amount and effectiveness of a substance that mimics an active ingredient in marijuana, but that is produced by the body's own nerve cells.

Medicine & Health / Neuroscience

created Aug 06, 2010 | popularity 5 / 5 (3) | comments 4 | with audio podcast

Gene May Hold Key to Reducing Spread of Oral Cancers

(PhysOrg.com) -- The spread of cancer cells in the tongue may be reduced if a gene that regulates cancer cell migration can be controlled, according to new research at the University of Illinois at Chicago.

Medicine & Health / Cancer

created Jul 23, 2010 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Taking aim at metastatic lung tumors

A new study uses a sophisticated genomic analysis to unravel some of the complex cellular signals that drive the deadly invasive spread of lung cancer. The research, published by Cell Press in the June issue of the journal ...

Medicine & Health / Cancer

created Jun 14, 2010 | popularity not rated yet | comments 0

Anti-cancer Agent Stops Metastasis in its Tracks

(PhysOrg.com) -- Like microscopic inchworms, cancer cells slink away from tumors to travel and settle elsewhere in the body. Now, researchers at Weill Cornell Medical College report in today’s online edition of the journal ...

Medicine & Health / Cancer

created Apr 14, 2010 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Why metastasic cells migrate

Migration ability of metastatic cells is not due to an altered mechanism of tumor cells but to a natural capacity of healthy cells. The results could help to identify potential strategies for metastasis inhibition.

Medicine & Health / Cancer

created Mar 29, 2010 | popularity 4.5 / 5 (2) | comments 0

Human cells exhibit foraging behavior like bacteria

(PhysOrg.com) -- When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found.

Biology / Cell & Microbiology

created Mar 17, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

A paracrine pathway regulates pancreatic cancer cell invasion

Pancreatic cancer cell invasion along nerves is regulated by a paracrine pathway that involves glial cell-derived neurotrophic factor, which may be a possible target for preventing the invasion, according to a new study published ...

Medicine & Health / Cancer

created Jan 13, 2010 | popularity not rated yet | comments 0

Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis

Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...

Medicine & Health / Cancer

created Nov 25, 2009 | popularity not rated yet | comments 0

Reactive oxygen's role in metastasis

Researchers at the Burnham Institute for Medical Research have discovered that reactive oxygen species, such as superoxide and hydrogen peroxide, play a key role in forming invadopodia, cellular protrusions implicated in ...

Medicine & Health / Cancer

created Sep 16, 2009 | popularity not rated yet | comments 0

Researchers identify key factor that stimulates brain cancer cells to spread

Researchers funded by the National Institutes of Health have found that the activity of a protein in brain cells helps stimulate the spread of an aggressive brain cancer called glioblastoma multiforme (GBM). In a move toward ...

Medicine & Health / Cancer

created Aug 18, 2009 | popularity 5 / 5 (3) | comments 0

Carbohydrate acts as tumor suppressor

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. These ...

Medicine & Health / Cancer

created Jul 06, 2009 | popularity 5 / 5 (4) | comments 1

Researchers describe function of key protein in cancer spread

Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread ...

Chemistry / Biochemistry

created May 21, 2009 | popularity 4.5 / 5 (2) | comments 0

Metastasis-promoting protein identified; could provide a prognostic test or target for breast cancer

Tumors that are about to progress and metastasize go through a process also seen in normal embryonic development, known as the epithelial to mesenchymal transition (EMT). Tumor cells revert to a less-differentiated state, ...

Medicine & Health / Cancer

created Feb 23, 2009 | popularity 5 / 5 (1) | comments 0