News tagged with transcription factors

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Regulating hematopoietic differentiation

Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms ...

Oct 05, 2012
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Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, ...

Sep 25, 2012
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Deciphering the language of transcription factors

Transcription factors are proteins that bind to DNA to promote or suppress protein production. Since almost all diseases involve disruption of the protein-production process, transcription factors are promising biological ...

Sep 11, 2012
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The controlled cell

(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the ...

Sep 07, 2012
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Controlling inflammatory and immune responses

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation. This important breakthrough will be published in tomorrow's print edition ...

Jul 12, 2012
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