News tagged with therapeutic strategy

Researchers solve structure of human protein critical for silencing genes

In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the pr ...

Biology / Cell & Microbiology

created May 25, 2012 | popularity 4.8 / 5 (8) | comments 0 | with audio podcast

An 'immortal' devil's genome and the secrets of a cancer that's catching

Researchers reporting in the February 17th issue of the Cell Press journal Cell have sequenced the complete genome of one immortal devil. The genomes of the Tasmanian devil and its transmissible cancer may he ...

Biology / Biotechnology

created Feb 16, 2012 | popularity 4.7 / 5 (11) | comments 11 | with audio podcast

Visualization of DNA synthesis in vivo

Researchers of the University of Zurich have discovered a new substance for labeling and visualization of DNA synthesis in whole animals. Applications for this technique include identifying the sites of virus ...

Chemistry / Biochemistry

created Dec 13, 2011 | popularity 5 / 5 (1) | comments 0

Subset of self-destructive immune cells may selectively drive diabetes

New research identifies a distinctive population of immune cells that may play a key role in the pathogenesis of diabetes. The research, published by Cell Press and available online in the April 21st issue of Immunity, sheds ...

Medicine & Health / Medical research

created Apr 21, 2011 | popularity 5 / 5 (1) | comments 0

Computer modeling used to study protein involved with cancer, aging and chronic disease

(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...

Chemistry / Biochemistry

created Apr 13, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers use zebrafish to identify new gene linked to melanoma

Thanks to the zebrafish, there is new hope for people with melanoma, an aggressive skin cancer that is responsible for approximately 8,700 deaths each year in the United States.

Medicine & Health / Genetics

created Apr 05, 2011 | popularity not rated yet | comments 0 | with audio podcast

New cause of blindness discovered by scientists

University of Manchester scientists have discovered a new cause of age-related macular degeneration (AMD), a condition that affects more than 50 million people worldwide and results in blindness.

Chemistry / Biochemistry

created Sep 21, 2010 | popularity not rated yet | comments 0

How the parasite responsible for severe forms of malaria can resist a major antimalarial agent

French esearchers from CNRS, INSERM and Toulouse University Hospital have demonstrated how the parasite Plasmodium falciparum, which causes severe forms of malaria, is able to circumvent the action of artemisinin ...

Medicine & Health / Medical research

created May 05, 2010 | popularity not rated yet | comments 0

Treatment resistance in some cancer cells may be reversible

(PhysOrg.com) -- The ability of cancer cells to resist treatment with either targeted drug therapies or traditional chemotherapy may, in some cases, result from a transient state of reversible drug "tolerance." ...

Medicine & Health / Cancer

created Apr 01, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers use drug-radiation combo to eradicate lung cancer

Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.

Medicine & Health / Cancer

created Oct 29, 2009 | popularity 5 / 5 (5) | comments 0

STAT3 protein found to play a key role in cancer

A protein called STAT3 has been found to play a fundamental role in converting normal cells to cancerous cells, according to a new study led by David E. Levy, Ph.D., professor of pathology and microbiology at NYU Langone ...

Medicine & Health / Cancer

created Jun 25, 2009 | popularity not rated yet | comments 0

A new take on growth factor signaling in tamoxifen resistance

Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...

Medicine & Health / Genetics

created Jun 24, 2009 | popularity not rated yet | comments 0

Researchers discover pathway with implications for obesity

(PhysOrg.com) -- Cornell scientists have discovered how two related proteins and their roles in a key molecular pathway are critical to creating obesity-causing fat cells.

Medicine & Health / Medical research

created Jun 03, 2009 | popularity not rated yet | comments 0

Key to future medical breakthroughs is systems biology, say leading European scientists

Crucial breakthroughs in the treatment of many common diseases such as diabetes and Parkinson's could be achieved by harnessing a powerful scientific approach called systems biology, according to leading scientists from across ...

Medicine & Health / Medical research

created Jan 13, 2009 | popularity 5 / 5 (2) | comments 0