News tagged with therapeutic gene

Nanochannel electroporation: Researchers do precise gene therapy without a needle

For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle.

Nanotechnology / Bio & Medicine

created Oct 16, 2011 | popularity 5 / 5 (15) | comments 1 | with audio podcast

One shot of gene therapy and children with congenital blindness can now see

Born with a retinal disease that made him legally blind, and would eventually leave him totally sightless, the nine-year-old boy used to sit in the back of the classroom, relying on the large print on an electronic ...

Medicine & Health / Medical research

created Oct 25, 2009 | popularity 5 / 5 (23) | comments 1

Researchers solve structure of human protein critical for silencing genes

In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the pr ...

Biology / Cell & Microbiology

created May 25, 2012 | popularity 4.8 / 5 (8) | comments 0 | with audio podcast

An 'immortal' devil's genome and the secrets of a cancer that's catching

Researchers reporting in the February 17th issue of the Cell Press journal Cell have sequenced the complete genome of one immortal devil. The genomes of the Tasmanian devil and its transmissible cancer may he ...

Biology / Biotechnology

created Feb 16, 2012 | popularity 4.7 / 5 (11) | comments 11 | with audio podcast

Researchers develop CAD-Type tools for engineering RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the Joint BioEnergy ...

Biology / Biotechnology

created Dec 22, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Genome editing, a next step in genetic therapy, corrects hemophilia in animals

Using an innovative gene therapy technique called genome editing that hones in on the precise location of mutated DNA, scientists have treated the blood clotting disorder hemophilia in mice. This is the first time that genome ...

Biology / Biotechnology

created Jun 26, 2011 | popularity 5 / 5 (6) | comments 2 | with audio podcast

In Parkinson's disease, brain cells abandon mitochondria

In a study that sheds new light on the causes of Parkinson's disease, researchers report that brain cells in Parkinson's patients abandon their energy-producing machinery, the mitochondria. A shutdown in fuel can have devastating ...

Medicine & Health / Medical research

created Oct 06, 2010 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Rare variants in gene coding may up risk of autoimmune disorders

(PhysOrg.com) -- Rare variants in the gene coding of an enzyme that controls the activity of a key immune cell occur more often in people with autoimmune disorders like rheumatoid arthritis and type 1 diabetes, ...

Medicine & Health / Genetics

created Jul 01, 2010 | popularity 5 / 5 (2) | comments 0

Treatment resistance in some cancer cells may be reversible

(PhysOrg.com) -- The ability of cancer cells to resist treatment with either targeted drug therapies or traditional chemotherapy may, in some cases, result from a transient state of reversible drug "tolerance." ...

Medicine & Health / Cancer

created Apr 01, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

STAT3 protein found to play a key role in cancer

A protein called STAT3 has been found to play a fundamental role in converting normal cells to cancerous cells, according to a new study led by David E. Levy, Ph.D., professor of pathology and microbiology at NYU Langone ...

Medicine & Health / Cancer

created Jun 25, 2009 | popularity not rated yet | comments 0

Biologists Discover How 'Silent' Mutations Influence Protein Production

(PhysOrg.com) -- Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. ...

Biology / Cell & Microbiology

created Apr 09, 2009 | popularity 5 / 5 (2) | comments 1

First description of a triple DNA helix in a vacuum

A team of researchers at the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC) have managed for the first time to extract trustworthy structural information ...

Chemistry / Biochemistry

created Apr 18, 2012 | popularity 4.2 / 5 (6) | comments 0

Researchers publish paper on CHO-K1 cell genome sequencing

The Chinese Hamster Ovary (CHO) cell is one of the most preferred hosts used to manufacture therapeutic proteins -- genes that are added to "cell factories" to produce proteins that are later turned into medicines. 

Biology / Biotechnology

created Aug 05, 2011 | popularity not rated yet | comments 0

New technology provides first view of DNA damage within entire human genome

New technology providing the first view of DNA damage throughout the entire human genome developed by Cardiff University scientists could offer a valuable new insight into the development and treatment of conditions like ...

Medicine & Health / Genetics

created Jan 18, 2011 | popularity 4.5 / 5 (2) | comments 0

Second dose of gene therapy for inherited blindness proves safe in animal studies

Gene therapy for a severe inherited blindness, which produced dramatic improvements last year in 12 children and young adults who received the treatment in a clinical trial, has cleared another hurdle. The ...

Medicine & Health / Genetics

created Mar 03, 2010 | popularity not rated yet | comments 0