Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.
Cell & Microbiology
8 hours ago
0
19
We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury. Chromosomes, which carry all of our genetic instructions, must be copied ...
Molecular & Computational biology
Apr 11, 2024
0
68
Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres that protect the ends ...
Molecular & Computational biology
Feb 28, 2024
0
244
The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a way of differentiating ...
Cell & Microbiology
Feb 15, 2024
0
64
A team from Children's Medical Research Institute has discovered a new way to impair cancer cell growth, which could lead to the development of a new class of cancer therapeutics with minimal side-effects on normal cells.
Cell & Microbiology
Dec 8, 2023
0
30
A new study finds that greenspace—the vegetation in a neighborhood's yards, parks and public spaces—has a positive impact on a key genetic marker associated with exposure to stress. However, the study also finds that ...
Ecology
Oct 18, 2023
0
51
The extraordinary lifespans of bats could be under threat from rising global temperatures, according to new research published in Proceedings of the Royal Society B: Biological Sciences.
Plants & Animals
Oct 17, 2023
0
20
Researchers have determined a new feature of how the natural ends of our chromosomes are protected from harmful outcomes.
Cell & Microbiology
Aug 17, 2023
0
164
Similar to the expeditions of a hundred or two hundred years ago, the Tara Pacific expedition lasted over two years. Its goal was to research the conditions for life and survival of corals. The ship crossed the entire Pacific ...
Plants & Animals
Jun 26, 2023
0
63
Is it possible to extend lifespan by simply slowing the aging of an organ, such as the intestine? CNRS researchers have discovered how to extend the life expectancy of zebrafish by reactivating a gene within intestinal cells. ...
Cell & Microbiology
May 22, 2023
0
448
