Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year. For effective treatment, patients ...
Cell & Microbiology
Sep 14, 2022
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128
Researchers have identified how the bacterium that causes tuberculosis (TB) can evolve rapidly in response to new environments, according to a study published today in eLife.
Evolution
Jun 21, 2022
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135
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey ...
Cell & Microbiology
Feb 22, 2021
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53
People who fall sick with drug-resistant tuberculosis (TB) face daunting odds. Only about two in three survive the illness, unlike people with drug-sensitive TB, of whom more than 90 percent survive.
Molecular & Computational biology
Sep 17, 2018
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15
Tuberculosis, a lung disease that spreads in the air through coughs or sneezes, now kills more people worldwide than any other infectious agent, according to the World Health Organization's latest global tuberculosis report. ...
Biochemistry
Jun 1, 2018
1
25
Subgroups of tuberculosis (TB)-causing bacteria can persist even when antibiotics wipe out most of the overall population. The need to eliminate these persistent subpopulations is one reason why TB treatment regimens are ...
Cell & Microbiology
May 31, 2017
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109
Researchers at the Francis Crick Institute have discovered that the bacterium responsible for tuberculosis (TB) can hide and live on inside the very immune cells that are sent to hunt and kill it.
Cell & Microbiology
Feb 28, 2017
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43
Tuberculosis (TB) remains one of deadliest infectious diseases of humans, killing 50% of individuals when left untreated. Even today, TB causes 1-2 million deaths every year mainly in developing countries. Multidrug-resistance ...
Biotechnology
Sep 1, 2013
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0
(Medical Xpress)—Researchers at the University of Pittsburgh Graduate School of Public Health have identified an enzyme that will trigger the rapid breakdown of several mycobacteria species, including the bacteria known ...
Biochemistry
Jan 8, 2013
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0
Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant ...
Cell & Microbiology
Oct 25, 2012
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