The development of pharmaceutical treatments is difficult—clinicians and researchers know a certain drug can regulate particular functions, but they might not know how it actually works. Researchers at Tokyo University ...
Materials Science
Feb 1, 2021
0
11
A new method of identifying molecular targets to fight disease could help accelerate future drug development new Griffith University research published in Scientific Reports has found.
Cell & Microbiology
Jan 27, 2021
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17
Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...
Biochemistry
Dec 15, 2020
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49
Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units. These oligoureas, which ...
Biochemistry
Dec 7, 2020
1
9
Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism.
Molecular & Computational biology
Nov 11, 2020
0
214
A research team led by Nagoya University scientists in Japan has developed an approach that can quickly find synthetic proteins that specifically bind to important targets, such as components of the SARS-CoV-2 virus. The ...
Biochemistry
Oct 7, 2020
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40
An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit (MRC-IEU) at the University of Bristol, has demonstrated how genetic data can be used to support drug target ...
Biotechnology
Sep 7, 2020
0
56
A team of scientists at the Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) have developed a method for visualizing microtubule dynamics and cell membrane protein endocytosis in living plant cells, ...
Plants & Animals
Aug 21, 2020
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58
At the start of a COVID-19 infection, the coronavirus SARS-CoV-2 docks onto human cells using the spike-like proteins on its surface. The spike protein is at the centre of vaccine development because it triggers an immune ...
Cell & Microbiology
Aug 18, 2020
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386
A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly ...
Cell & Microbiology
Aug 13, 2020
0
312
