News tagged with target proteins

Infectious disease may have shaped human origins, study says

Roughly 100,000 years ago, human evolution reached a mysterious bottleneck: Our ancestors had been reduced to perhaps five to ten thousand individuals living in Africa. In time, "behaviorally modern" humans ...

Biology / Evolution

created 36 minutes ago | popularity 5 / 5 (1) | comments 0 | with audio podcast

Jarid2 may break the Polycomb silence

Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a ...

Biology / Cell & Microbiology

created Apr 30, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Molding the business end of neurotoxins

For snakes, spiders, and other venomous creatures, the "business end," or active part, of a toxin is the area on the surface of a protein that is most likely to undergo rapid evolution in response to environmental constraints, ...

Biology / Cell & Microbiology

created Feb 23, 2012 | popularity not rated yet | comments 0

Scientists characterize protein essential to survival of malaria parasite

A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.

Chemistry / Biochemistry

created Jan 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists reveal how bacteria build homes inside healthy cells

(PhysOrg.com) -- Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.

Biology / Cell & Microbiology

created Dec 20, 2011 | popularity not rated yet | comments 0 | with audio podcast

Study identifies a key molecular switch for telomere extension by telomerase

Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...

Biology / Cell & Microbiology

created Nov 23, 2011 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Opening the data bank -- scientists try to match new protein structures

Imagine playing Go Fish with 3,000 cards. Scientists at Rochester Institute of Technology and Dowling College are engaged in a similar game with higher stakes. Instead of cards, they are matching the protein to the job it ...

Biology / Cell & Microbiology

created Nov 07, 2011 | popularity 5 / 5 (1) | comments 0

Microbiologists identify two molecules that kill lymphoma cells in mice

Researchers at the University of Southern California have identified two molecules that may be more effective cancer killers than are currently available on the market.

Biology / Cell & Microbiology

created Nov 06, 2011 | popularity 5 / 5 (5) | comments 2 | with audio podcast

Biodesign researchers to develop new reagent pipeline for molecular medicine

An ongoing Arizona State University effort to develop a revolutionary class of reagents that holds great promise for the future of medicine has received a major boost with a three-year, $4 million award from ...

Biology / Biotechnology

created Oct 24, 2011 | popularity 5 / 5 (3) | comments 0

X-rays help advance the battle against heart disease

(PhysOrg.com) -- Scientists from Imperial College London and Diamond Light Source have revealed the structure of a cholesterol-lowering-drug target. Published in the journal Nature, this finding could lead ...

Chemistry / Biochemistry

created Oct 06, 2011 | popularity not rated yet | comments 0

We are not only eating 'materials', we are also eating 'information'

In a new study, Chen-Yu Zhang's group at Nanjing university present a rather striking finding that plant miRNAs could make into the host blood and tissues via the route of food-intake. Moreover, once inside the host, they ...

Biology / Cell & Microbiology

created Sep 19, 2011 | popularity 4.8 / 5 (8) | comments 4

Research team achieves first 2-color STED microscopy of living cells

Researchers are able to achieve extremely high-resolution microscopy through a process known as stimulated emission depletion (STED) microscopy. This cutting-edge imaging system has pushed the performance of microscopes significantly ...

Physics / Optics & Photonics

created Aug 17, 2011 | popularity 5 / 5 (1) | comments 0

Researchers work to identify how crops may be vulnerable to attack

On farmland around the globe, a silent war rages, between crops and the diseases that attack them. Crop diseases cost the world an estimated $220 billion every year and put millions at risk of starvation.

Biology / Biotechnology

created Jul 29, 2011 | popularity not rated yet | comments 0

Scientists design nano-sized drug transporter to fight disease

Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.

Nanotechnology / Bio & Medicine

created Jul 26, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Researchers design a better way to discover drug candidates

(PhysOrg.com) -- Yale researchers have devised a novel way to trick cells into getting rid of problematic proteins, a method that could help pharmaceutical companies quickly identify promising targets for new drugs.

Chemistry / Biochemistry

created Jul 04, 2011 | popularity 4 / 5 (2) | comments 0 | with audio podcast