'Decoding' gene regulation

Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...

A new role for zebrafish: Larger scale gene function studies

A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National ...

Genetic molecular mechanisms of neural development identified

Neural development is an extremely complex and highly orchestrated process, involving genetic cascades during which dozens of genes are activated at specific times and places. Polycomb-group (PcG) proteins play an important ...

Gene transfer optimization

Controlled gene transfer into different target cells by means of specific surface markers is significantly more efficient than gene transfer without this assistance. Gene therapies using lentiviral transfer of genetic information ...

Turning off the 'aging genes'

Restricting calorie consumption is one of the few proven ways to combat aging. Though the underlying mechanism is unknown, calorie restriction has been shown to prolong lifespan in yeast, worms, flies, monkeys, and, in some ...

Protein essential for maintaining beta cell function identified

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 – a beta-cell enriched transcription factor – is ...

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