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News tagged with tamiflu

Drug to fight tumors also fights the flu and possibly other viruses

Ever get a flu shot and still get the flu? If so, there's new hope for flu-free winters in the years to come thanks to a new discovery by researchers who found that a drug called DMXAA, originally developed as anti-tumor ...

Medicine & Health / Medications

created Feb 28, 2011 | popularity 5 / 5 (1) | comments 0

Flu: Drugs stockpile an option for rich countries, not poor

Stockpiling antiviral drugs as a weapon against pandemic flu saves lives but, when measured as a tool for averting economic damage, is an option only open to rich countries, a study published on Wednesday said.

Medicine & Health / Diseases, Conditions, Syndromes

created Feb 02, 2011 | popularity not rated yet | comments 0

Call for full access to Tamiflu trial data to allow for independent scrutiny

Leading researchers today call for access to all clinical trial data (published and unpublished) to allow drugs to be independently assessed by the scientific community.

Medicine & Health / Medications

created Jan 11, 2011 | popularity 5 / 5 (2) | comments 0

Tamiflu is more effective at relieving flu symptoms than a combination of tamiflu and relenza: study

In adults with seasonal influenza A virus infection, the combination of the drugs oseltamivir (tamiflu) and zanamivir (relenza) is less effective than oseltamivir monotherapy and not significantly more effective than zanamivir ...

Medicine & Health / Medications

created Nov 02, 2010 | popularity not rated yet | comments 0

Swine flu patients benefited from taking Tamiflu, says study

Healthy people who caught swine flu during the 2009 pandemic may have been protected against developing radiographically (x-ray) confirmed pneumonia by taking the antiviral drug oseltamivir (Tamiflu), concludes a study of ...

Medicine & Health / Diseases, Conditions, Syndromes

created Sep 29, 2010 | popularity 1 / 5 (1) | comments 0

Antibody may help treat and prevent influenza outbreaks

Researchers have discovered a monoclonal antibody that is effective against "Avian" H5N1, seasonal H1N1 and the 2009 "Swine" H1N1 influenza. Scientists at Sea Lane Biotechnologies, LLC, in collaboration with Mt. Sinai School ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jul 08, 2010 | popularity not rated yet | comments 0

Biologists provide molecular explanation for the evolution of Tamiflu resistance

Biologists at the California Institute of Technology have pinpointed molecular changes that helped allow the global spread of resistance to the antiviral medication Tamiflu (oseltamivir) among strains of the seasonal H1N1 ...

Chemistry / Biochemistry

created Jun 03, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Expert panel to view confidential swine flu papers

(AP) -- An expert panel investigating the World Health Organization's response to last year's swine flu outbreak said Wednesday it wants to see confidential exchanges between the U.N. body and drug companies.

Medicine & Health / Diseases, Conditions, Syndromes

created May 19, 2010 | popularity not rated yet | comments 0

Study finds that drugs used for treatment of influenza in pregnancy appear to be safe

Tamiflu and two other drugs used to treat influenza appear safe for pregnant women and their babies, researchers at UT Southwestern Medical Center have found in a retrospective study of 239 cases of women who received the ...

Medicine & Health / Medications

created Apr 27, 2010 | popularity not rated yet | comments 0

Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu

If the behavior of the seasonal form of the H1N1 influenza virus is any indication, scientists say that chances are good that most strains of the pandemic H1N1 flu virus will become resistant to Tamiflu, the main drug stockpiled ...

Medicine & Health / Diseases, Conditions, Syndromes

created Mar 01, 2010 | popularity not rated yet | comments 0 | with audio podcast

Gastrointestinal absorption of Tamiflu in critically ill patients with H1N1

An increased dosage of Tamiflu (oseltamivir) for patients with critical illness is unlikely to be required in the treatment of pandemic (H1N1) influenza, contrary to current international guidelines, found a new study in ...

Medicine & Health / Other

created Feb 16, 2010 | popularity not rated yet | comments 0

Disease severity in H1N1 patients

A new study published in CMAJ (Canadian Medical Association Journal) concerning the severity of H1N1 influenza has found that admissions to an intensive care unit (ICU) were associated with a longer interval between sympto ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jan 21, 2010 | popularity not rated yet | comments 0

Toward a less expensive version of the anti-flu drug Tamiflu

Scientists have developed an alternative method for producing the active ingredient in Tamiflu®, the mainstay for fighting H1N1 and other forms of influenza. The new process could expand availability of the ...

Chemistry / Analytical Chemistry

created Jan 13, 2010 | popularity not rated yet | comments 0

Drug-resistant swine flu cluster on Vietnam train

(PhysOrg.com) -- A cluster of seven people infected with a Tamiflu-resistant strain of pandemic H1N1 influenza has been identified in Vietnam by a team including Oxford researchers.

Medicine & Health / Diseases, Conditions, Syndromes

created Dec 09, 2009 | popularity not rated yet | comments 0

British researchers: little evidence Tamiflu works

(AP) -- British researchers say there is little evidence Tamiflu stops complications in healthy people who catch the flu, though public health officials contend the swine flu drug reduces flu hospitalizations and deaths.

Medicine & Health / Medications

created Dec 08, 2009 | popularity not rated yet | comments 0

Oseltamivir

Oseltamivir (INN) (pronounced /ɒsəlˈtæmɨvɪr/) is a drug that blocks the influenza virus from spreading between cells in the body. Thus it is an antiviral drug that is used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B infection. Like zanamivir, oseltamivir is a neuraminidase inhibitor. It acts as a transition-state analogue inhibitor of influenza neuraminidase, preventing progeny virions from detaching from infected cells.

Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by US-based Gilead Sciences and is currently marketed by Hoffmann–La Roche (Roche) under the trade name Tamiflu. In Japan, it is marketed by Chugai Pharmaceutical Co., which is more than 50% owned by Roche. Oseltamivir is generally available by prescription only.

Roche estimates that 50 million people have been treated with oseltamivir. The majority of these have been in Japan, where an estimated 35 million have been treated. Since June 2009, Roche has been forced to allow other companies to develop competing drugs to Tamiflu, after much speculation about Roche's so-called 'monopoly' of Tamiflu in the UK.[citation needed]

For more information about Oseltamivir, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: influenza