A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
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46
For patients with certain types of cancer, CAR T cell therapy has been nothing short of life changing. Developed in part by Carl June, Richard W. Vague Professor at the Perelman School of Medicine, and approved by the Food ...
Bio & Medicine
Mar 25, 2024
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47
Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating ...
Bio & Medicine
Mar 15, 2024
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7
Cell therapies for cancer can be potentially enhanced using a CRISPR RNA-editing platform, according to a new study published Feb. 21 in Cell.
Cell & Microbiology
Feb 21, 2024
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70
Researchers at the Pritzker School of Molecular Engineering and the Department of Chemistry at the University of Chicago have engineered tiny, spinning micro-robots that bind to immune cells to probe their function. The robot, ...
Bio & Medicine
Feb 21, 2024
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6
Toxoplasmosis is an infectious disease found worldwide, caused by the single-celled parasite Toxoplasma gondii. In humans, infection poses a particular risk to pregnant women, as it can lead to birth defects. Like the closely ...
Evolution
Feb 16, 2024
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71
Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.
Biotechnology
Feb 1, 2024
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112
Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency. ...
Cell & Microbiology
Jan 7, 2024
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98
Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced ...
Molecular & Computational biology
Dec 1, 2023
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35
In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases. But the lack of effective ways to deliver ...
Bio & Medicine
Nov 27, 2023
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3
T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.
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