Since the completion of the Human Genome Project, which identified nearly 20,000 protein-coding genes, scientists have been trying to decipher the roles of those genes. A new approach developed at MIT, the Broad Institute, ...
Biotechnology
Dec 12, 2013
0
0
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a ...
Biochemistry
Jun 4, 2009
0
0
The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. ...
Cell & Microbiology
Mar 2, 2011
0
1
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical ...
Cell & Microbiology
Dec 11, 2019
0
91
A protein that is crucial for regulating the self-renewal of normal prostate stem cells, needed to repair injured cells or restore normal cells killed by hormone withdrawal therapy for cancer, also aids the transformation ...
Cell & Microbiology
Dec 2, 2010
0
0
Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or in the planning stages. A new study led by ...
Biotechnology
Dec 11, 2017
0
104
Regenerative medicine could one day allow physicians to correct congenital deformities, regrow damaged fingers, or even mend a broken heart. But to do it, they will have to reckon with the body's own anti-cancer security ...
Biotechnology
Nov 18, 2015
1
75
A landmark study by Florida State University biologists, in collaboration with scientists in Britain, is the first to identify a life-or-death "cell competition" process in mammalian tissue that suppresses cancer by causing ...
Biotechnology
Jul 13, 2010
0
0
(Phys.org)—Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.
Biochemistry
Dec 12, 2012
0
0
Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Bio & Medicine
Apr 20, 2009
0
0
