Directly reprogramming a cell's identity with gene editing
Researchers have used CRISPR—a revolutionary new genetic engineering technique—to convert cells isolated from mouse connective tissue directly into neuronal cells.
Aug 11, 2016
in
Key molecular signal that shapes regeneration in planarian stem cells discovered
Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts. Scientists ...
First report on efficient reprogramming of diabetic foot ulcer cells to create therapeutic stem cell
The potential to use a patient's own cells to treat non-healing chronic wounds - a serious complication of diabetes - took an important step forward as researchers successfully reprogrammed skin cells taken from diabetic ...
Stem cells of worms and humans more similar than expected
The transient form of genetic information, the RNA, is processed in a similar manner in the cells of both organisms. These mechanisms seem to be at work throughout the whole animal kingdom. Scientists from the Max Delbrück ...
New tool enables researchers to rapidly manipulate protein levels in mammalian cells
A research team headed by investigators at the Icahn School of Medicine at Mount Sinai (ISMMS) has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell. They say the method, ...
Breakthrough in understanding how stem cells become specialized
Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have made a major advance in understanding how the cells of an organism, which all contain the same genetic information, come to be so diverse. A study ...
Scientists develop new way to measure important chemical modification on RNA
A team of scientists including researchers from UCLA has developed an RNA sequencing technique that provides detailed information about a chemical modification that occurs on RNA and plays an important role in pluripotent ...
Scientists discover a way to create specialized cells more efficiently
Researchers at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered that a metabolic molecule called alpha-ketoglutarate helps pluripotent stem cells mature early in the process ...
Two proteins safeguard skin stem cells
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days. A study led by ICREA ...
Tuned gels reveal molecules that drive stem cell differentiation
By monitoring stem cell differentiation on gels that mimic the stiffness and nanofibrous structure of biological tissue, researchers have identified the specific molecules that stem cells use when selecting bone and cartilage ...
