A study from Patrick Matthias and his group at the FMI challenges a widely accepted model on how epigenome dynamics control the differentiation of hematopoietic cells. The plasticity of pluripotent stem cells was thought ...
Cell & Microbiology
Oct 20, 2015
0
50
UC San Francisco researchers have for the first time developed a method to precisely control embryonic stem cell differentiation with beams of light, enabling them to be transformed into neurons in response to a precise external ...
Cell & Microbiology
Aug 26, 2015
0
65
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer, ...
Biotechnology
Jul 28, 2015
4
443
Imagine someone hands you a smoothie and asks you to identify everything that went into it.
Biotechnology
May 21, 2015
0
544
A novel analytical method has enabled Whitehead Institute scientists to identify a regulatory gene required for breast stem cells to differentiate. Inhibition of this gene, known as RUNX1, prevents cells from exiting the ...
Cell & Microbiology
May 7, 2015
0
93
The human body is a cross between a factory and a construction zone—at least on the cellular level. Certain proteins act as project managers, which direct a wide variety of processes and determine the fate of the cell as ...
Biochemistry
Apr 29, 2015
0
1134
Imagine a pair of twins that everyone believed to be estranged, who turn out to be closer than anyone knew. A genetic version of this heartwarming tale might be taking place in our cells. We and other mammals have two copies ...
Cell & Microbiology
Mar 5, 2015
0
57
When it comes to gene expression - the process by which our DNA provides the recipe used to direct the synthesis of proteins and other molecules that we need for development and survival - scientists have so far studied one ...
Biotechnology
Mar 4, 2015
0
39
Using a comprehensive analysis of RNA expression in different cell types, scientists from the RIKEN-led FANTOM5 consortium have made major strides toward resolving an outstanding mystery in biology. In the work, published ...
Cell & Microbiology
Feb 12, 2015
0
19
After using optical tweezers to squeeze a tiny bead attached to the outside of a human stem cell, researchers now know how mechanical forces can trigger a key signaling pathway in the cells.
Cell & Microbiology
Feb 10, 2015
0
611
