News tagged with statins
Gene test shows who could benefit from statins to reduce colon cancer risk
A genetic test can help determine in which patients cholesterol-lowering statin drugs might have the most benefit in also reducing the risk of colorectal cancer, a new study from researchers at the University of Michigan ...
Apr 19, 2010 |
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Researchers Find Statins Increase Risk of Diabetes
(PhysOrg.com) -- Statins increase the risk of diabetes, but the absolute risk is low - especially when compared with a reduction in coronary events, a Glasgow academic has found.
Medicine & Health / Diseases, Conditions, Syndromes
Feb 17, 2010 |
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Common Gene Mutation Linked to Statin Side Effects
(PhysOrg.com) -- Common genetic mutations may help explain why some people develop side effects that lead to discontinuing the use of cholesterol-lowering statins. Duke University Medical Center researchers who identified ...
Oct 13, 2009 |
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Statins may treat blood vessel disorder that can lead to fatal strokes
In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis ...
Medicine & Health / Medical research
Jan 26, 2009 |
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NIH stops study of niacin to prevent heart attacks
(AP) -- Disappointing news: A drug that raises people's so-called good cholesterol didn't go on to prevent heart attacks.
Medicine & Health / Medications
May 26, 2011 |
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Pneumonia death rate lower among people who take statins
Taking statins could help prevent people dying from pneumonia, according to a study by the London School of Hygiene and Tropical Medicine.
Medicine & Health / Diseases, Conditions, Syndromes
Apr 05, 2011 |
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Inflammation behind heart valve disease
Research from Karolinska Institutet in Sweden shows, that a specific inflammatory factor may be important in the development of the heart valve disease aortic stenosis. The results suggest that anti-inflammatory medication ...
Medicine & Health / Medical research
Mar 15, 2011 |
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Statin benefit 'not affected' by low inflammation
(PhysOrg.com) -- A new Oxford-led study shows that statins are at least as effective in reducing the risk of heart attack or stroke in patients with low levels of inflammation as they are in other patients.
Medicine & Health / Medical research
Jan 28, 2011 |
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Statins: Benefits questionable in low-risk patients
There is not enough evidence to recommend the widespread use of statins in people with no previous history of heart disease, according to a new Cochrane Systematic Review. Researchers say statins should be prescribed with c ...
Medicine & Health / Medical research
Jan 19, 2011 |
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Statin risks may outweigh benefits for patients with a history of brain hemorrhage
A computer decision model suggests that for patients with a history of bleeding within the brain, the risk of recurrence associated with statin treatment may outweigh the benefit of the drug in preventing cardiovascular disease, ...
Medicine & Health / Neuroscience
Jan 10, 2011 |
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Statins less dangerous than thought for liver patients
Long-term use of statins, a drug widely prescribed to prevent artery-blocking cholesterol, is less risky than thought for patients with a common form of liver disease, according to a study published on Wednesday by The La ...
Medicine & Health / Medical research
Nov 24, 2010 |
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Long-term statin use is unlikely to increase cancer risk: study
Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention ...
Nov 09, 2010 |
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Statins did not reduce colorectal cancer in WHI analysis
The use of statins among a group of postmenopausal women did not reduce the risk for colorectal cancer, according to the results of a prospective analysis of data from the large population-based Women's Health Initiative ...
Nov 08, 2010 |
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Wider statin use could be cost-effective preventive measure, study finds
A new analysis suggests that broader statin use among adult patients may be a cost-effective way to prevent heart attack and stroke. The Stanford University School of Medicine study also found that using a popular test - ...
Medicine & Health / Medical research
Sep 27, 2010 |
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Cholesterol drug may have role in treating prostate cancer
A drug commonly prescribed for people with high cholesterol may also be effective in treating prostate cancer, according to new research by Dr. Xiao-Yan Wen at St. Michael's Hospital.
Sep 20, 2010 |
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Statin
The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.
They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.
For more information about Statin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
