News tagged with statins
Team sequencing 1,000 fungal genomes
A 79-year-old collection of fungal cultures and the U.S. Forest Service's Northern Research Station are part of a team that will sequence 1,000 fungal genomes in the next 5 years.
Nov 07, 2011 |
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NIH stops study of niacin to prevent heart attacks
(AP) -- Disappointing news: A drug that raises people's so-called good cholesterol didn't go on to prevent heart attacks.
Medicine & Health / Medications
May 26, 2011 |
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Pneumonia death rate lower among people who take statins
Taking statins could help prevent people dying from pneumonia, according to a study by the London School of Hygiene and Tropical Medicine.
Medicine & Health / Diseases, Conditions, Syndromes
Apr 05, 2011 |
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Despite uncertain benefit, fibrates commonly used in US, Canada
Although recent evidence suggests that the clinical benefit may be uncertain for fibrates, a class of drugs used for the treatment of high lipid levels, use of these drugs is common in the U.S. and Canada, with usage increasing ...
Medicine & Health / Medications
Mar 22, 2011 |
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Inflammation behind heart valve disease
Research from Karolinska Institutet in Sweden shows, that a specific inflammatory factor may be important in the development of the heart valve disease aortic stenosis. The results suggest that anti-inflammatory medication ...
Medicine & Health / Medical research
Mar 15, 2011 |
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Trial suggests statin may affect markers associated with progression of HIV
A recent multicenter clinical trial of atorvastatin, a type of cholesterol-lowering drug, found that although the drug did not inhibit plasma HIV RNA levels, it did inhibit expression of cellular markers of immune activation ...
Medicine & Health / HIV & AIDS
Feb 16, 2011 |
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Heart patients should be referred to cardiac rehabilitation before leaving hospital
Healthcare practitioners can increase the number of patients with heart disease referred to a cardiac rehabilitation program by 40 per cent, helping them to reduce their risk of dying and improve their quality of life, say ...
Feb 14, 2011 |
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Statin benefit 'not affected' by low inflammation
(PhysOrg.com) -- A new Oxford-led study shows that statins are at least as effective in reducing the risk of heart attack or stroke in patients with low levels of inflammation as they are in other patients.
Medicine & Health / Medical research
Jan 28, 2011 |
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Statins: Benefits questionable in low-risk patients
There is not enough evidence to recommend the widespread use of statins in people with no previous history of heart disease, according to a new Cochrane Systematic Review. Researchers say statins should be prescribed with c ...
Medicine & Health / Medical research
Jan 19, 2011 |
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A pounding heart may be dangerous for some kidney patients
Among older adults with a recent heart attack (myocardial infarction), those with lower levels of kidney function are less likely to take their medications as prescribed, according to a study appearing in an upcoming issue ...
Medicine & Health / Diseases, Conditions, Syndromes
Jan 13, 2011 |
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Statin risks may outweigh benefits for patients with a history of brain hemorrhage
A computer decision model suggests that for patients with a history of bleeding within the brain, the risk of recurrence associated with statin treatment may outweigh the benefit of the drug in preventing cardiovascular disease, ...
Medicine & Health / Neuroscience
Jan 10, 2011 |
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Statins less dangerous than thought for liver patients
Long-term use of statins, a drug widely prescribed to prevent artery-blocking cholesterol, is less risky than thought for patients with a common form of liver disease, according to a study published on Wednesday by The La ...
Medicine & Health / Medical research
Nov 24, 2010 |
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Long-term statin use is unlikely to increase cancer risk: study
Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention ...
Nov 09, 2010 |
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Statins did not reduce colorectal cancer in WHI analysis
The use of statins among a group of postmenopausal women did not reduce the risk for colorectal cancer, according to the results of a prospective analysis of data from the large population-based Women's Health Initiative ...
Nov 08, 2010 |
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Eliminating or reducing cost-sharing for high-value prescription drugs improves medication use
An initiative by the U. S. technology company Pitney Bowes to make medications of proven value less expensive for their employees succeeded in stabilizing employees' adherence to their treatment regimens, according to a Commonwealth ...
Nov 02, 2010 |
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Statin
The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.
They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.
For more information about Statin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
