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News tagged with splicing

Of yeast and men: Unraveling the molecular mechanisms of Friedreich's ataxia

Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...

Biology / Cell & Microbiology

created Jul 09, 2009 | popularity 4 / 5 (1) | comments 0

Getting more from whole-transcript microarrays

The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...

Biology / Other

created May 21, 2009 | popularity not rated yet | comments 0

Scientists discover master regulator of motor neuron firing

(PhysOrg.com) -- When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ...

Medicine & Health / Neuroscience

created Mar 16, 2009 | popularity 4.7 / 5 (3) | comments 0

Siestas Among the Drosophilae

(PhysOrg.com) -- Isaac Edery is concerned with biological clocks, internal mechanisms that enable virtually all plants and animals to behave in rhythmic biological cycles known as circadian rhythms.

Biology /

created Jan 28, 2009 | popularity not rated yet | comments 0

Scientists clarify editing error underlying genetic neurodegenerative disease

Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...

Biology /

created Jan 28, 2009 | popularity 5 / 5 (3) | comments 0

Researchers find mechanism underlying alt. splicing of premessenger RNA into messenger RNA

An international research team led by Tim Nilsen, Ph.D., a professor of medicine and biochemistry and the director of the School of Medicine's Center for RNA Molecular Biology, has discovered an unexpected mechanism governing ...

Biology /

created Dec 24, 2008 | popularity 5 / 5 (2) | comments 1