Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity is unexpectedly difficult. A team of ...
Cell & Microbiology
Nov 13, 2017
0
155
An international scientific consortium including the Freiburg plant biologist Prof. Dr. Thomas Laux has discovered a regulatory pathway that turns plants' ordinary somatic cells into germ cells for sexual reproduction. The ...
Cell & Microbiology
Jun 8, 2017
0
3
A team of researchers, led by a plant cell biologist at the University of California, Riverside, has for the first time identified a small RNA species and its target gene that together regulate female germline formation in ...
Biotechnology
May 25, 2017
0
8
University of Tsukuba-led researchers explored the function of the reprogramming factor KLF4 in production of induced pluripotent stem cells (iPSCs). KLF4 was shown to bind upstream of the Tcl1 target gene, which controls ...
Cell & Microbiology
Mar 8, 2017
0
31
Germline cells are the only cells that develop into eggs or sperm, while somatic cells develop into the body. Progenitors of the germline, known as primordial germ cells (PGCs), differentiate into eggs or sperm after embryonic ...
Cell & Microbiology
Jan 23, 2017
0
4
As socioeconomic inequality grows, the publicly acknowledged importance of traits such as honesty, loyalty, self-sacrifice, and reciprocity appears to have fallen out of favor with some of our socio-economic and political ...
Other
Dec 27, 2016
47
40
In various vertebrate species, including fish, amphibians, reptiles, birds and mammals, the DMRT1 gene is a master sex regulator, working to develop and maintain 'maleness' -either the sex cells (or germline) into testis ...
Evolution
Dec 6, 2016
0
351
To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in. A research group at the University of Basel now describes for the first time a mechanism by which hippocampal ...
Cell & Microbiology
Aug 18, 2016
0
59
Before mRNA can be used by ribosomes as a guide to build proteins, it has to undergo a series of processing steps. This includes getting a series of adenine (A) nucleotides added by poly(A) polymerase to one of the mRNA's ...
Cell & Microbiology
May 5, 2016
0
10
In a new Cell Reports paper, a team led by John P. Cooke, M.D., Ph.D., of the Houston Methodist Research Institute, has identified and characterized a biological factor critical to the transformation of adult somatic cells ...
Cell & Microbiology
Apr 21, 2016
0
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