One step closer to artificial rhino eggs

To prevent the extinction of the northern white rhino, the international consortium BioRescue is attempting to create artificial egg cells from stem cells. A team led by MDC's Sebastian Diecke and Micha Drukker of Leiden ...

Studying diseases with better delivery of gene-editing tools

Stem cells can be used to study the effects of disease on numerous tissue types due to their pluripotency, or ability to produce cells of any type. But using gene-editing tools with them can be challenging, according to Xiaojun ...

Landing therapeutic genes safely in the human genome

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...

Modeling how cells choose their fates

It may seem hard to believe, but each one of us began as a single cell that proliferated into the trillions of cells that make up our bodies. Though each of our cells has the exact same genetic information, each also performs ...

Natural killer cells coordinate wound healing

Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds. If the healing process is accelerated, the immune ...

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