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News tagged with sirna

Nanoparticle-delivered RNA interference drug stops head and neck cancer growth

(Phys.org) -- A nanoparticle drug delivery vehicle for small interfering RNA molecules (siRNA), that is already being tested in human clinical trials, now shows promise for the treatment of head and neck cancer. Dong Shin, ...

Nanotechnology / Bio & Medicine

created Apr 06, 2012 | popularity 5 / 5 (8) | comments 1 | with audio podcast

PRINTed nanoparticles deliver multiple punches to treat prostate cancer

Using technologies common to the semiconductor industry, a team of investigators at the University of North Carolina at Chapel Hill and Liquidia Technologies has created a polymer nanoparticle that can encapsulate large loads ...

Nanotechnology / Bio & Medicine

created Jan 21, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gold nanorods could improve radiation therapy of head and neck cancer

Radiation therapy is an important part of head and neck cancer therapy, but most head and neck tumors have a built-in mechanism that makes them resistant to radiation. As a result, oncologists have to deliver huge doses of ...

Nanotechnology / Bio & Medicine

created Jan 20, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Scientists design nano-sized drug transporter to fight disease

Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.

Nanotechnology / Bio & Medicine

created Jul 26, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Nanoparticle therapeutics might help people suffering from hearing disorders

For millions of people hearing disorders make a negative impact on their lives. Scientists are looking into new ways of treating hearing disorders, by using different sorts of nanoparticles as original inner ear delivery ...

Nanotechnology / Bio & Medicine

created Jun 13, 2011 | popularity 4 / 5 (1) | comments 0

Gene knockout shows potential for diabetes-related heart failure

Silencing the TLR4 gene can stop the process which may lead to cardiovascular disease in diabetic patients. Researchers writing in BioMed Central's open access Journal of Translational Medicine carried out a series of in ...

Medicine & Health / Medical research

created Dec 10, 2010 | popularity not rated yet | comments 0

Image-guided breast cancer therapy enabled by nanodrug

By combining an iron oxide nanoparticle, a tumor-targeting peptide, and a therapeutic nucleic acid into one construct, a team of investigators from the Massachusetts General Hospital and Harvard Medical School have created ...

Nanotechnology / Bio & Medicine

created Oct 28, 2010 | popularity 1 / 5 (1) | comments 0 | with audio podcast

Understanding how cells respond to nanoparticles

Gold nanoparticles are showing real promise as vehicles for efficiently delivering therapeutic nucleic acids, such as disease-fighting genes and small interfering RNA (siRNA) molecules, to tumors. Now, a team of investigators ...

Nanotechnology / Bio & Medicine

created Oct 28, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find gene-silencing nanoparticles may put end to pesky summer pest

Summer just wouldn't be complete without mosquitoes nipping at exposed skin. Or would it? Research conducted by a Kansas State University team may help solve a problem that scientists and pest controllers have been itching ...

Nanotechnology / Bio & Medicine

created Jul 19, 2010 | popularity 4.6 / 5 (5) | comments 8 | with audio podcast

Multistage nanovector system provides sustained delivery of siRNA cancer therapeutic in mice

New research by scientists at The University of Texas Health Science Center at Houston (UTHealth) and The University of Texas M. D. Anderson Cancer Center could make it easier for patients to use a family of promising experimental ...

Medicine & Health / Cancer

created May 05, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Magnetic Nanoworms and Nanocrystals Deliver siRNA to Tumors

(PhysOrg.com) -- Small pieces of nucleic acid known as short interfering RNAs, or siRNAs, can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs ...

Nanotechnology / Bio & Medicine

created Sep 23, 2009 | popularity not rated yet | comments 0

Strong immune response to new siRNA drugs in development may cause toxic side effects

Small synthetic fragments of genetic material called small interfering RNA (siRNA) can block production of abnormal proteins; however, these exciting new drug candidates can also induce a strong immune response, causing toxic ...

Medicine & Health / Medical research

created May 20, 2009 | popularity 4 / 5 (1) | comments 0