News tagged with signal pathways

What makes stem cells tick?

Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...

Biology / Cell & Microbiology

created Aug 06, 2009 | popularity 5 / 5 (3) | comments 0

Cannibalistic cells may help prevent infections

Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection.

Medicine & Health / Medical research

created Aug 03, 2009 | popularity not rated yet | comments 0

Researchers discover new molecular pathway for targeting cancer, disease

(PhysOrg.com) -- A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new ...

Medicine & Health / Cancer

created Jul 20, 2009 | popularity 5 / 5 (1) | comments 1

Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow

Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long ...

Medicine & Health / Cancer

created Jul 06, 2009 | popularity not rated yet | comments 0

A new take on growth factor signaling in tamoxifen resistance

Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...

Medicine & Health / Genetics

created Jun 24, 2009 | popularity not rated yet | comments 0

Fate in fly sensory organ precursor cells could explain human immune disorder

(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...

Biology / Cell & Microbiology

created Jun 21, 2009 | popularity 5 / 5 (1) | comments 0

Why the thumb of the right hand is on the left hand side

It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia ...

Biology / Cell & Microbiology

created May 22, 2009 | popularity 4.8 / 5 (13) | comments 0

Brain mechanisms for behavioral flexibility

New research provides insight into how the brain can execute different actions in response to the same stimulus. The study, published by Cell Press in the April 16 issue of the journal Neuron, suggests that i ...

Medicine & Health / Neuroscience

created Apr 15, 2009 | popularity 4.8 / 5 (5) | comments 0

Research sheds new light on inflammatory disease

Scientists at the University of Liverpool have found that understanding the precise timing of communication between cells that coordinate the body's response to disease could be key to new drug developments.

Medicine & Health / Medical research

created Apr 09, 2009 | popularity 5 / 5 (4) | comments 0

New insight into an old reaction: Adenylylation regulates cell signaling

A new study reveals the importance of adenylylation in the regulation of cell signaling from bacteria to higher organisms. The research, published by Cell Press in the April 10th issue of the journal Molecular Cell, provid ...

Biology / Cell & Microbiology

created Apr 09, 2009 | popularity 4 / 5 (1) | comments 0

New method for detection of phosphoproteins reveals regulator of melanoma invasion

Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell ...

Medicine & Health / Medical research

created Apr 09, 2009 | popularity 5 / 5 (2) | comments 0

High-fat diets plus extra protein make for bad mix

It's basically a given that diets loaded with fat can lead to considerable health problems. But a new study in the April issue of Cell Metabolism, a Cell Press publication, shows that in some cases diets that are high in bot ...

Biology / Cell & Microbiology

created Apr 07, 2009 | popularity 4 / 5 (6) | comments 0

When intestinal bacteria go surfing

The bacterium Escherichia coli is part of the healthy human intestinal flora. However, E. coli also has pathogenic relatives that trigger diarrhea illnesses: enterohemorrhagic E.coli bacteria. During the course of an inf ...

Biology / Cell & Microbiology

created Mar 19, 2009 | popularity 5 / 5 (1) | comments 0

New target for heart failure therapy identified

A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers.

Medicine & Health / Medical research

created Mar 16, 2009 | popularity 1 / 5 (1) | comments 0

New investigational treatment for bladder cancer

A team of researchers, led by Columbia University Medical Center faculty, has identified a new investigational therapy for the treatment of bladder cancer. The discovery was made using a new research model, using mice, which ...

Medicine & Health / Cancer

created Mar 12, 2009 | popularity not rated yet | comments 0