Researchers from the University of Edinburgh, Scotland, and the University of Cantabria, Spain, have teamed up to develop an AI trained to discover senolytic medicinal chemistry in familiar compounds.
Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. ...
Cell & Microbiology
Jul 18, 2022
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86
Cellular senescence—when a cell can no longer divide—is a programmed stage in a cell's life cycle. Sometimes, as in aging, we wish it didn't happen so much and sometimes, as in cancer, we wish it would happen more. Given ...
Cell & Microbiology
Feb 5, 2016
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841
Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury. To cope with such ...
Cell & Microbiology
Feb 22, 2024
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90
A study at the University of Cologne's CECAD Cluster of Excellence in Aging Research has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. ...
Cell & Microbiology
Feb 2, 2024
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102
Similar to the way expanding companies increase their work forces, cells must boost their production of internal biomolecules when they grow in size in order to stay healthy. In the 1970s, biologists showed that this scaled-up ...
Cell & Microbiology
Jan 29, 2024
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20
Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell; for example, mitochondria power ...
Cell & Microbiology
Jan 1, 2024
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121
With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, ...
Cell & Microbiology
Dec 4, 2023
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57
Naked mole-rats have the longest life span among all rodents and can resist aging and the age-related diseases. However, the precise mechanisms underlying this ability are largely unclear.
Cell & Microbiology
Aug 18, 2023
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36
Insights into healing and aging were discovered by National Institutes of Health researchers and their collaborators, who studied how a tiny sea creature regenerates an entire new body from only its mouth. The researchers ...
Cell & Microbiology
Jun 30, 2023
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