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Chemical reaction design goes virtual

Researchers at the Institute for Chemical Reaction Design and Discovery and Hokkaido University have developed a virtual ligand-assisted (VLA) screening method that could drastically reduce the amount of trial and error required ...

Super scintillators enable X-ray detection at an ultralow level

The introduction of lead-free metal halide powder into a scintillation screen took some tinkering. Once a KAUST team worked out the right technique, they were able to produce an exceptionally efficient, robust and flexible ...

New system speeds screening of drug-delivering nanoparticles

James Dahlman and Phil Santangelo are helping to define an evolving era in medicine, one in which messenger ribonucleic acid—mRNA—can be delivered directly to cells to fight against disease. And their latest groundbreaking ...

Molecular mechanism involved in the cholesterol cell transport

A team of the University of Barcelona (UB) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) identified a mechanism involved in the movement of cholesterol inside the cells. The study, published in the Journal ...

Deep-learning algorithm aims to accelerate protein engineering

Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...

Regulators for extracellular vesicle production

Biological vesicles are nano-sized containers that transport proteins and other substances within or between cells. Most cells release so-called extracellular vesicles (EVs), which play important roles in cell-to-cell communication. ...

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