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News tagged with rnai

Scientists find the structure of a key 'gene silencer' protein

Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise ...

Chemistry / Biochemistry

created Apr 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Using plants to silence insect genes in a high-throughput manner

Scientists at the Max Planck Institute for Chemical Ecology, Germany, are now using a procedure which brings forward ecological research on insects: They study gene functions in moth larvae by manipulating ...

Biology / Biotechnology

created Feb 02, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Researchers solve a protein complex's molecular structure to explain its role in gene silencing

A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA ...

Biology / Cell & Microbiology

created Nov 13, 2011 | popularity not rated yet | comments 0 | with audio podcast

Study reveals new role for RNA interference during chromosomal replication

At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...

Biology / Cell & Microbiology

created Oct 16, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Seizing control of South American parasite

Scientists battling Leishmania, a parasite second only to malaria in the number of deaths it causes, have identified an important vulnerability in the genetic code of one major parasite strain.

Medicine & Health / Diseases, Conditions, Syndromes

created Nov 19, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study reveals how a common virus eludes the immune system

Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-m ...

Biology / Cell & Microbiology

created Aug 31, 2009 | popularity not rated yet | comments 0

Hitting cancer where it hurts

Two studies in the May 29th issue of Cell, a Cell Press publication, have taken advantage of new technological advances to search for and find previously unknown weaknesses in a hard to treat form of cancer. The discoveries lend n ...

Medicine & Health / Cancer

created May 28, 2009 | popularity 5 / 5 (1) | comments 0

The future of personalized cancer treatment: An entirely new direction for RNAi delivery

In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, ...

Biology / Biotechnology

created May 17, 2009 | popularity 5 / 5 (6) | comments 1

A new gene silencing platform -- silence is golden

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches. This may enable the development and discovery of a new ...

Biology /

created Feb 15, 2009 | popularity 4 / 5 (1) | comments 0