Researchers at the Whitehead Institute and Memorial Sloan-Kettering Cancer Center have defined and analyzed the crystal structure of a yeast Argonaute protein bound to RNA. This complex plays a key role in the RNA interference ...
Jun 20, 2012
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Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise ...
Apr 26, 2012
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Scientists at the Max Planck Institute for Chemical Ecology, Germany, are now using a procedure which brings forward ecological research on insects: They study gene functions in moth larvae by manipulating ...
Feb 02, 2012
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A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA ...
Nov 13, 2011
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At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Oct 16, 2011
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Scientists battling Leishmania, a parasite second only to malaria in the number of deaths it causes, have identified an important vulnerability in the genetic code of one major parasite strain.
Nov 19, 2010
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Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-m ...
Aug 31, 2009
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Two studies in the May 29th issue of Cell, a Cell Press publication, have taken advantage of new technological advances to search for and find previously unknown weaknesses in a hard to treat form of cancer. The discoveries lend n ...
May 28, 2009
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In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, ...
May 17, 2009
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A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches. This may enable the development and discovery of a new ...
Feb 15, 2009
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