Mapping the 3-D geometry of SARS-CoV-2's genome

The novel coronavirus uses structures within its RNA to infect cells. Scientists have now identified these configurations, generating the most comprehensive atlas to date of SARS-CoV-2's genome.

Scientists uncover pivotal virus structure for replication

Researchers from the Monash Biomedicine Discovery Institute (BDI) have revealed the structure of a protein complex that is essential for the poliovirus to replicate. The structure may be similar to those in other RNA viruses ...

Universal virus detection platform to expedite viral diagnosis

The quick, accurate detection of a virus on a wide scale is the key to combating infectious diseases such as COVID-19. A new viral diagnostic strategy using reactive polymer-grafted, double-stranded RNAs will serve as a pre-screening ...

New method captures early viral-host protein interactions

More than 70% of all viruses known to cause human disease, including the one that causes COVID-19, are RNA viruses. They invade the body by hijacking the internal machinery of cells. Yet little is known about how viral RNA ...

Making sense of the viral multiverse

In November of 2019—likely, even earlier—a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale. Within a few months, the relentless voyager known ...

New coronavirus (SARS-CoV-2) mapped out

Jean and Peter Medawar wrote in 1977 that a virus is "simply a piece of bad news wrapped up in proteins." The 'bad news' in the SARS-CoV-2 case is the new coronavirus carries its mysterious genome in the form of a very long ...

Stuttering DNA orchestrates the start of the mosquito's life

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ...

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