A that gene provides both protection and destruction

The family of ENDOU enzymes is found in most organisms, yet its functions are only poorly understood. In humans, it has been connected with cancer. RNA viruses, such as SARS-CoV2, contain a gene corresponding to ENDOU, and ...

Researchers uncover viral small RNAs in mosquito cells

Researchers from Boston University School of Medicine (BUSM) provide a new genomics resource that details the small RNA transcriptomes (gene expression) of four bio-medically important mosquito species.

How epithelial cells ward off viruses

A team led by LMU's Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. This recognition process subsequently induces a potent ...

Gut microbiome manipulation could result from virus discovery

Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells—a finding that could be used to control the composition of the gut microbiome, which is important for human health.

Study identifies new 'hidden' gene in COVID-19 virus

Researchers have discovered a new "hidden" gene in SARS-CoV-2—the virus that causes COVID-19—that may have contributed to its unique biology and pandemic potential. In a virus that only has about 15 genes in total, knowing ...

Breaking COVID-19's 'clutch' to stop its spread

Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from ...

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