Two opposing teams battle it out to regulate gene expression on the DNA playing field. One, the activators, keeps DNA open to enzymes that transcribe DNA into RNA. Their repressor opponents antagonize that effort by twisting ...
Cell & Microbiology
Aug 26, 2012
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0
A novel insecticide targets a specific gene in a pest, killing only that bug species on crops and avoiding collateral damage to beneficial insects caused by today's pesticides.
Cell & Microbiology
Jul 21, 2015
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360
One challenge in killing off harmful bacteria is that many of them develop a resistance to antibiotics. Researchers at the University of Rochester are targeting the formation of the protein-making machinery in those cells ...
Cell & Microbiology
Sep 7, 2014
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0
X chromosomes are very special genetic material. They differ in number between men and women. To achieve equality between sexes, one out of two X chromosomes in women is silenced. In flies, the opposite happens: in male flies, ...
Cell & Microbiology
Jul 25, 2013
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Challenging the dogma of what scientists thought they understood about DNA viruses, a team of researchers led by Children's Hospital of Philadelphia (CHOP) has shown that adenovirus uses its own efficient RNA splicing mechanisms ...
Molecular & Computational biology
Oct 21, 2021
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68
Whether revealing a perpetrator with DNA evidence, diagnosing a pathogen, classifying a paleontological discovery, or determining paternity, the duplication of nucleic acids (amplification) is indispensable. In the journal ...
Biochemistry
Mar 12, 2019
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115
DNA may have appeared on Earth earlier than has hitherto been assumed. LMU chemists led by Oliver Trapp show that a simple reaction pathway could have given rise to DNA subunits on the early Earth.
Biochemistry
Jun 18, 2019
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8
Numerous biological processes depend on molecules called lariat RNAs (LaRNAs). These lasso-shaped structures form in the cell during RNA splicing. During this process, transcribed RNA strands convert to messenger RNA before ...
Biochemistry
May 24, 2012
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0
(Phys.org)—In a soundproofed, vibration-stabilized, temperature-controlled room, Stanford biophysicist Steven Block was watching a very small origami project.
Biochemistry
Oct 22, 2012
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0
Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide ...
Biotechnology
Jan 5, 2021
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