News tagged with rna splicing

Engineered molecule changes itself to detect and attack diseased cells

(PhysOrg.com) -- Assistant Professor of Bioengineering Christina Smolke has engineered biological molecules that regulate a cell's behavior by adjusting their own forms and functions in response to the internal conditions ...

Biology / Biotechnology

created Nov 30, 2010 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Research uncovers new exception to decades-old rule about RNA splicing

There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...

Biology / Biotechnology

created May 17, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

The splice of life: Proteins cooperate to regulate gene splicing

Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease – much like editing film can change a movie scene. Abnormal variations in splicing ...

Biology / Biotechnology

created Feb 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

New mechanism in the regulation of human genes

Scientists at the Technical University of Munich and the Helmholtz Zentrum Muenchen and along with their colleagues from the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Centre for Genomic Regulation ...

Biology / Cell & Microbiology

created Jul 14, 2011 | popularity not rated yet | comments 1 | with audio podcast

Lasers, custom microscope show gene splicing process in real time

From neurosurgery to bar code readers, lasers have been used in a myriad of applications since they were first introduced in the late 1950's. Now, with the work being done in Jeff Gelles' Lab at Brandeis University, ...

Biology / Cell & Microbiology

created Mar 10, 2011 | popularity not rated yet | comments 0 | with audio podcast

Spying on a cellular director in the cutting room

Like a film director cutting out extraneous footage to create a blockbuster, the cellular machine called the spliceosome snips out unwanted stretches of genetic material and joins the remaining pieces to fashion a template ...

Biology / Cell & Microbiology

created Mar 21, 2010 | popularity not rated yet | comments 0 | with audio podcast

Possible help in fight against muscle-wasting disease (w/ Video)

(PhysOrg.com) -- A compound already used to treat pneumonia could become a new therapy for an inherited muscular wasting disease, according to researchers at the University of Oregon and the University of ...

Medicine & Health / Medical research

created Nov 06, 2009 | popularity not rated yet | comments 0

Scientists discover master regulator of motor neuron firing

(PhysOrg.com) -- When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ...

Medicine & Health / Neuroscience

created Mar 16, 2009 | popularity 4.7 / 5 (3) | comments 0

Siestas Among the Drosophilae

(PhysOrg.com) -- Isaac Edery is concerned with biological clocks, internal mechanisms that enable virtually all plants and animals to behave in rhythmic biological cycles known as circadian rhythms.

Biology /

created Jan 28, 2009 | popularity not rated yet | comments 0

Scientists clarify editing error underlying genetic neurodegenerative disease

Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...

Biology /

created Jan 28, 2009 | popularity 5 / 5 (3) | comments 0

Real-time monitoring of RNA splicing in living cells moves step closer with novel fluorescent probe

Numerous biological processes depend on molecules called lariat RNAs (LaRNAs). These lasso-shaped structures form in the cell during RNA splicing. During this process, transcribed RNA strands convert to messenger ...

Chemistry / Biochemistry

created May 24, 2012 | popularity not rated yet | comments 0

Genetic mutation linked to lethal disease

Researchers have identified a genetic mutation found in the Ohio Amish population as the cause of a fatal developmental disease in fetuses and infants, according to research published in the April 8, 2011, issue of Science.

Medicine & Health / Genetics

created Apr 18, 2011 | popularity not rated yet | comments 0

Cancer-associated long non-coding RNA regulates pre-mRNA splicing

Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...

Biology / Cell & Microbiology

created Sep 23, 2010 | popularity 5 / 5 (1) | comments 0

Gladstone scientists identify role of key protein in ALS and frontotemporal dementia

Scientists at the Gladstone Institute of Neurological Disease (GIND) have identified the reason a key protein plays a major role in two neurodegenerative diseases. In the current edition of the Journal of Neuroscience, re ...

Medicine & Health / Neuroscience

created Jan 12, 2010 | popularity not rated yet | comments 0

Researchers identify drug candidate for treating spinal muscular atrophy

A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA), a currently incurable disease that is the leading genetic cause of death in infants. This is the finding of ...

Medicine & Health / Medical research

created Nov 04, 2009 | popularity not rated yet | comments 0