Lariats are discarded byproducts of RNA splicing, the process by which genetic instructions for making proteins are assembled. A new study has found hundreds more lariats than ever before, yielding new information about how ...
Cell & Microbiology
Jun 17, 2012
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0
In a recent paper in RNA Biology, researchers show that mitochondria translocate their key RNA methyltransferase enzyme, TRMT1, into host cell nuclei in response to neural activity. This subcellular relocalization of key ...
A tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that cause many of the worst cases of meningitis.
Biotechnology
Feb 15, 2018
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377
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing ...
Molecular & Computational biology
Aug 15, 2023
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54
RNA is the key functional component of spliceosomes, molecular machines that control how genes are expressed, report scientists from the University of Chicago online, Nov. 6 in Nature. The discovery establishes that RNA, ...
Cell & Microbiology
Nov 6, 2013
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1
On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein. This process, known as alternative splicing, allows a single gene to ...
Molecular & Computational biology
Jan 20, 2023
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168
A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance ...
Cell & Microbiology
Nov 10, 2013
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(Phys.org)—A team of researchers with the University of California has learned more about the process that is involved during CRISPR/Cas9 gene splicing by using a crystallization technique to get a closer look. In their ...
When genes were first discovered, the canonical view was that each gene encodes a unique protein. However, biologists later found that segments of genes can be combined in different ways, giving rise to many different proteins.
Evolution
Dec 21, 2012
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0
Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.
Cell & Microbiology
Sep 26, 2013
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