Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
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30
Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities of all proteins ...
Cell & Microbiology
Feb 5, 2019
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42
RNA sequencing is a powerful technology for studying cells and diseases. In particular, single-cell RNA sequencing helps uncover the heterogeneity and diversity of our body. This is the central technology of the "Human Cell ...
Biotechnology
Jun 1, 2021
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12
X chromosomes are very special genetic material. They differ in number between men and women. To achieve equality between sexes, one out of two X chromosomes in women is silenced. In flies, the opposite happens: in male flies, ...
Cell & Microbiology
Jul 25, 2013
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Researchers have been using "Fluorescence in situ hybridization" (FISH) analysis for decades to literally fish for specific DNA and RNA sequences in intact cells and tissues within their vast seas of nucleic acid molecules. ...
Biotechnology
May 20, 2019
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60
Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target. A better understanding of viral propagation and evolution in single cells ...
Biochemistry
Aug 20, 2020
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175
(Phys.org) —There's hope for patients with myotonic dystrophy. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause the disease in living ...
Biochemistry
Apr 30, 2013
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A recently described variety of RNA closely associated with gene expression was found to be largely cell-type specific, raising the possibility this variety of RNA sequences may be able to be used as a marker in stem cell ...
Cell & Microbiology
Aug 30, 2017
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28
In biology, as in real estate, location matters. Working copies of active genes—called messenger RNAs or mRNAs—are positioned strategically throughout living tissues, and their location often helps regulate how cells ...
Cell & Microbiology
Feb 27, 2014
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21
RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode proteins but act in gene ...
Cell & Microbiology
Apr 25, 2013
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