Embryonic development involves the tightly coordinated activity of thousands of genes, each switched on at a specific time and place in the growing organism under the control of regulatory DNA sequences called promoters. ...
Biotechnology
Nov 1, 2013
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(PhysOrg.com) -- A research team has made precise measurements of where and how RNA polymerase encounters obstacles while it reads nucleosomal DNA.
Cell & Microbiology
May 14, 2010
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Ligases are enzymes that serve critical functions in cells, helping to fuse together broken strands of DNA and RNA. These enzymes are also important bioengineering tools, useful in genetic sequencing, mutation detection and ...
Biochemistry
Oct 11, 2016
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There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
Biotechnology
May 17, 2012
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A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his ...
Cell & Microbiology
Aug 21, 2013
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(Phys.org) —Usually indigestion is a bad thing, but experiments by researcher Peter Chien and graduate student Robert Vass at the University of Massachusetts Amherst recently showed that for the bacteria Caulobacter crescentus, ...
Cell & Microbiology
Oct 31, 2013
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(PhysOrg.com) -- In a new study, researchers at the University of Illinois have identified and visualized the signaling pathways in protein-RNA complexes that help set the genetic code in all organisms. The genetic code allows ...
Biochemistry
Apr 14, 2009
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Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded researchers. Now, for the first ...
Cell & Microbiology
Jun 27, 2013
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(Phys.org)—A team of researchers with members from Washington University, Johns Hopkins School of Medicine, the Howard Hughes Medical Institute and the Polish Academy of Sciences has found that problems with RNA appear ...
A new UC San Francisco study highlights the potential importance of the vast majority of human DNA that lies outside of genes within the cell.
Biotechnology
Jun 26, 2013
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