CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.
Biotechnology
Jun 29, 2023
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15
UCLA researchers have developed an "all-in-one," next-generation statistical simulator capable of assimilating a wide range of information to generate realistic synthetic data and provide a benchmarking tool for medical and ...
Biotechnology
May 11, 2023
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65
RNA (ribonucleic acid) editing is an important process for maintaining essential functions of encoded proteins at the RNA level. Recent studies show that RNA editing is a widespread phenomenon that occurs in various land ...
Plants & Animals
May 9, 2023
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4
Single-cell RNA-sequencing (scRNA-seq) technologies offer the opportunity to understand regulatory mechanisms at single-cell resolution. Gene regulatory networks (GRNs) provide a crucial blueprint of regulatory mechanisms ...
Molecular & Computational biology
Apr 27, 2023
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2
Male beetles face a trade-off between competing with other males for mating opportunities and repairing damage to their sperm DNA, according to a study published April 4 in the open access journal PLOS Biology by Mareike ...
Plants & Animals
Apr 4, 2023
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119
Just as a flashlight casts a broader beam than the brightest candle when walking along a darkened trail, so too does long-read genomic sequencing seem to clarify a broader genomic picture of DNA mutations than short-read ...
Biotechnology
Mar 27, 2023
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46
Stanford University researchers have developed a computational method for identifying where cells are situated in a sample when capturing spatial transcriptomics. The method combines data from spatial transcriptions and a ...
How do cells work in a normal state? How do they change when they cause disease? Do they react as desired to new drugs? Nowadays, anyone seeking answers to these—and other related—questions in the laboratory can hardly ...
Cell & Microbiology
Mar 8, 2023
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13
Before 2020, when my friends and acquaintances asked me what I study as a molecular biologist, their eyes would inevitably glaze over as soon as I said "RNA." Now, as the COVID-19 pandemic has shown the power and promise ...
Cell & Microbiology
Mar 6, 2023
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136
Gene therapy is a potential mode of treatment for a wide variety of diseases caused by genetic mutations. While it has been an area of diverse and intense research, historically, only a very few patients have been treated ...
Bio & Medicine
Mar 2, 2023
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3
