Scientists make enzyme that could help explain origins of life
Mimicking natural evolution in a test tube, scientists at The Scripps Research Institute (TSRI) have devised an enzyme with a unique property that might have been crucial to the origin of life on Earth.
Vast gene-expression map yields neurological and environmental stress insights
(Phys.org) —A consortium led by scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) has conducted the largest survey yet of how information encoded in an ...
Better RNA interference, inspired by nature: New nanoparticles offer best-ever gene silencing
Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes.
Crowdsourced RNA designs outperform computer algorithms
An enthusiastic group of non-experts, working through an online interface and receiving feedback from lab experiments, has produced designs for RNA molecules that are consistently more successful than those generated by the ...
Researchers find a missing component in effort to create primitive, synthetic cells
A team of Massachusetts General Hospital (MGH) investigators working to create "protocells" – primitive synthetic cells consisting of a nucleic acid strand encased within a membrane-bound compartment – ...
Research sheds light on M.O. of unusual RNA molecules
(Phys.org) —The genes that code for proteins—more than 20,000 in total—make up only about 1 percent of the complete human genome. That entire thing—not just the genes, but also genetic junk and all ...
Researchers unveil first artificial enzyme created by evolution in test tube
(Phys.org)—There's a wobbly new biochemical structure in Burckhard Seelig's lab at the University of Minnesota that may resemble what enzymes looked like billions of years ago, when life on earth began ...
Early-Earth cells modeled to show how first life forms might have packaged RNA
(Phys.org)—Researchers at Penn State University have developed a chemical model that mimics a possible step in the formation of cellular life on Earth four-billion years ago. Using large "macromolecules" ...
Smallest, fastest-known RNA switches provide new drug targets
(Phys.org)—A University of Michigan biophysical chemist and his colleagues have discovered the smallest and fastest-known molecular switches made of RNA, the chemical cousin of DNA. The researchers say ...
Organic compounds found in proto-planetary disks
Simpler times: Did an earlier genetic molecule predate DNA and RNA?
(PhysOrg.com) -- In the chemistry of the living world, a pair of nucleic acidsDNA and RNAreign supreme. As carrier molecules of the genetic code, they provide all organisms with a mechanism for ...
Scientists find a way to make shRNA gene knockdown more effective
Scientists at Cold Spring Harbor Laboratory (CSHL) have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.
Jumping hurdles in the RNA world
Astrobiologists have shown that the formation of RNA from prebiotic reactions may not be as problematic as scientists once thought.
Researchers capture picture of microRNA in action
Biologists at The Scripps Research Institute (TSRI) have described the atomic-level workings of "microRNA" molecules, which control the expression of genes in all animals and plants.