News tagged with rna biology

Chemists Rationally Design Inhibitors Against an RNA Molecule that Causes Myotonic Muscular Dystrophy

(PhysOrg.com) -- Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular ...

Chemistry / Biochemistry

created Aug 07, 2009 | popularity 5 / 5 (3) | comments 0

Early evolution maximized the 'spellchecking' of protein sequences

As letters of the alphabet spell out words, when amino acids are linked to one another in a particular order they "spell out" proteins. But sometimes the cell machinery for building proteins in our bodies makes a mistake ...

Biology / Cell & Microbiology

created Aug 06, 2009 | popularity 4.6 / 5 (5) | comments 1

Professor sheds light on DNA mechanisms

By manipulating individual atoms in DNA and forming unique molecules, a Georgia State University researcher hopes to open new avenues in research towards better understanding the mechanisms of DNA replication and transcription, ...

Chemistry / Biochemistry

created Jul 17, 2009 | popularity 4.5 / 5 (2) | comments 0

Researchers see evidence of memory in the songbird brain

When a zebra finch hears a new song from a member of its own species, the experience changes gene expression in its brain in unexpected ways, researchers report. The sequential switching on and off of thousands ...

Biology / Plants & Animals

created Jun 26, 2009 | popularity 5 / 5 (1) | comments 0

MicroRNAs help control HIV life cycle

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, ...

Chemistry / Biochemistry

created Jun 25, 2009 | popularity 4 / 5 (1) | comments 0

Genetic switch potential key to new class of antibiotics

Researchers have determined the structure of a key genetic mechanism at work in bacteria, including some that are deadly to humans, in an important step toward the design of a new class of antibiotics, according to an accelerated ...

Chemistry / Biochemistry

created Apr 17, 2009 | popularity 5 / 5 (3) | comments 0

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality ...

Medicine & Health / Genetics

created Apr 09, 2009 | popularity not rated yet | comments 0

Small RNAs can play critical roles in male infertility/contraception

University of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant ...

Biology / Cell & Microbiology

created Apr 09, 2009 | popularity not rated yet | comments 0

Scientists discover master regulator of motor neuron firing

(PhysOrg.com) -- When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ...

Medicine & Health / Neuroscience

created Mar 16, 2009 | popularity 4.7 / 5 (3) | comments 0

Bacteria are models of efficiency

The bacterium Escherichia coli, one of the best-studied single-celled organisms around, is a master of industrial efficiency. This bacterium can be thought of as a factory with just one product: itself. It exists to make c ...

Biology /

created Feb 04, 2009 | popularity 4.5 / 5 (2) | comments 0

Scientists clarify editing error underlying genetic neurodegenerative disease

Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...

Biology /

created Jan 28, 2009 | popularity 5 / 5 (3) | comments 0

New method prevents microRNAs from escaping cells

(PhysOrg.com) -- MicroRNAs — one of the tiniest entities in the human genome — are great escape artists. Despite scientists’ best efforts to detect and capture them in different tissues, they often manage ...

Medicine & Health / Medical research

created Jan 26, 2009 | popularity 5 / 5 (1) | comments 0