SciLifeLab Fellow Alexey Amunts and his team together with researchers from the Czech Academy of Sciences report an assembly intermediate of the ribosome in mitochondria. It reveals 22 associated factors that cooperatively ...
Cell & Microbiology
Feb 16, 2021
0
97
The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells. These are mainly crystallines. If this dense packing cannot be maintained, for example ...
Molecular & Computational biology
Feb 10, 2021
1
14
Ribosomes are complex molecular machines in the cell that catalyze the production of proteins. Ahmed Badran, a Broad Fellow at the Broad Institute of MIT and Harvard, and his lab aim to engineer new kinds of ribosomes that ...
Biotechnology
Jan 27, 2021
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21
New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the cause—and possible solution—of antibiotic resistance.
Biochemistry
Jan 19, 2021
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230
Ribosomes are the complexes of ribonucleoproteins at the heart of protein synthesis in cells. However, in the absence of conclusive evidence, how these complexes operate has been open to debate. Now, Hirotatsu Imai and Noriyuki ...
Biochemistry
Jan 8, 2021
1
121
Protein synthesis is a finely tuned process in the cell by macromolecules known as ribosomes. Which regulators are responsible for controlling protein synthesis in the brain, and how do they exert their control on the ribosome? ...
Molecular & Computational biology
Dec 22, 2020
0
5
Ribosomes are the machines in the cell that use instructions from mRNA to synthesize functional proteins. There are hundreds of thousands of ribosomes in each cell, and they mostly process their instructions faithfully. But ...
Cell & Microbiology
Dec 17, 2020
0
15
Researchers at Karolinska Institutet characterize a GTPase involved in ribosome biogenesis in mitochondria. The study, published in Nucleic Acid Research, reveals new details of a complex process that enables mitochondria ...
Biotechnology
Dec 7, 2020
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13
Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly ...
Cell & Microbiology
Nov 23, 2020
0
63
Maturation of the ribosome is a complex operation. Work by an LMU team now shows that the 90S precursor of the small 40S subunit undergoes a "molting" process, during which it progressively discards its outermost components.
Molecular & Computational biology
Sep 22, 2020
0
24
