Maturation of the ribosome is a complex operation. Work by an LMU team now shows that the 90S precursor of the small 40S subunit undergoes a "molting" process, during which it progressively discards its outermost components.
Molecular & Computational biology
Sep 22, 2020
0
24
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
0
112
ETH Zurich researchers can predict how tightly a cell's protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different RNA sequences. This binding plays a key role in determining ...
Molecular & Computational biology
Aug 27, 2020
0
53
Researchers from Skoltech, Lomonosov Moscow State University and the Kharkevich Institute for Information Transmission Problems have studied the genomes of some 200 strains of bacteria to determine which proteins in the ribosome, ...
Evolution
Aug 11, 2020
1
0
When cells experience a high level of stress—for example, when they are exposed to too much UV light—ribosomes inside the cell collide and get into traffic jams. Now, Johns Hopkins scientists have found a protein that ...
Cell & Microbiology
Aug 5, 2020
0
128
Researchers from Munich and Ulm have determined how the pandemic coronavirus SARS-CoV-2 inhibits the synthesis of proteins in infected cells and shown that it effectively disarms the body's innate immune system.
Molecular & Computational biology
Jul 20, 2020
0
1002
The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more. Like a city, these structures require a ...
Cell & Microbiology
Jul 16, 2020
0
241
The stages in which ribosomes synthesize life-sustaining proteins have been revealed in unprecedented real-time detail by UMass Medical School structural biologists Andrei Korostelev, Ph.D., and Anna Loveland, Ph.D. Their ...
Molecular & Computational biology
Jul 2, 2020
0
16
mRNAs program the synthesis of proteins in cells, and their functional lifetimes are dynamically regulated. LMU researchers have now shown why blueprints that are more difficult to decipher have shorter lifetimes than others.
Molecular & Computational biology
Apr 17, 2020
0
92
After decades of speculation, researchers have demonstrated that a classical DNA repair enzyme also binds to RNA, affecting blood cell development.
Biotechnology
Feb 27, 2020
0
18
