Study reveals new clues about the architecture of X chromosomes

Researchers at Massachusetts General Hospital (MGH) have uncovered new clues that add to the growing understanding of how female mammals, including humans, 'silence' one X chromosome. Their new study, published in Molecular ...

New DNA modification 'signature' discovered in zebrafish

Researchers at the Garvan Institute of Medical Research have uncovered a new form of DNA modification in the genome of zebrafish, a vertebrate animal that shares an evolutionary ancestor with humans ~400 million years ago.

Tags on RNA silence X chromosome in females

The addition of a chemical tag on an RNA molecule is the critical switch that inactivates one X chromosome in every cell, ensuring healthy development in all female mammals, according to new research by Weill Cornell Medicine ...