News tagged with repair genes
Epigenetic signatures direct the repair potential of reprogrammed cells
A research team has identified epigenetic signatures, markers on DNA that control transient changes in gene expression, within reprogrammed skin cells. These signatures can predict the expression of a wound-healing protein ...
Mar 14, 2012 |
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A question of gene silencing
When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...
Aug 24, 2011 |
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Heads or tails? Worm with abundant ability to regenerate relies on ancient gene to make decisions
(PhysOrg.com) -- Most people don’t think worms are cool. But the tiny flatworm that Northwestern University scientist Christian Petersen studies can do something very cool indeed: it can regenerate itself from nearly ...
May 17, 2011 |
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Light, circadian rhythms affect vast range of physiological, behavioral functions
A new study of the genetic basis of circadian rhythms - the biological responses related to daily light exposure - has found that a few minutes of light exposure in a fungus directly affects a huge range of its biological ...
Medicine & Health / Medical research
Aug 26, 2010 |
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Protein made by breast cancer gene purified
A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, the protein produced by ...
Aug 22, 2010 |
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New drug reduces tumor size in women with advanced hereditary ovarian or breast cancer
Understanding the underlying genetic weakness of certain types of cancer may lead to targeted therapy and provide the key to effective treatment, a new study suggests. An international consortium of researchers has shown ...
Aug 12, 2010 |
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Researchers identify a new breast and ovarian cancer susceptibility gene
A group of researchers report evidence unambiguously implicating the gene RAD51C in susceptibility to breast and ovarian cancer. This gene normally plays a role in DNA repair. By screening RAD51C in unrelated individuals ...
Apr 21, 2010 |
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Survival of the healthiest: Selective eradication of malignant cells
The ultimate goal in cancer research, a treatment that kills cancer cells whilst leaving healthy cells untouched, is brought nearer by the success of a new therapeutic approach. The potential therapy, published in BioMed ...
Nov 05, 2009 |
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Gene therapy repairs injured human donor lungs for the first time
For the first time, scientists in the McEwen Centre for Regenerative Medicine, University Health Network have successfully used gene therapy to repair injured human donor lungs, making them potentially suitable ...
Medicine & Health / Medical research
Oct 28, 2009 |
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Researchers discover RNA repair system in bacteria
In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be ...
Oct 12, 2009 |
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Gene assay to help to predict lung cancer treatment resistance
The genes that may contribute to drug resistance in non-small cell lung cancer (NSCLC) can be predicted. Researchers writing in the open access journal BMC Cancer found good correlation between genes believed to be involv ...
Aug 26, 2009 |
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Protein plays unexpected role protecting chromosome tips
A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction ...
Aug 13, 2009 |
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Genetically engineered mice yield clues to 'knocking out' cancer
Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. ...
Jul 01, 2009 |
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Researchers Identify New Protein Important in Breast Cancer Gene's Role in DNA Repair
(PhysOrg.com) -- For years, researchers have known that under normal conditions, the breast cancer protein BRCA1 orchestrates the repair of damaged DNA, but the details of just how BRCA1 moves to the damaged ...
Mar 17, 2009 |
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DNA differences may influence risk of Hodgkin disease
A new analysis has found that certain variations in genes that repair DNA can affect a person's risk of developing Hodgkin disease. Published in the April 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer ...
Mar 09, 2009 |
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