News tagged with repair enzymes

Biochemists identify new genetic code repair tool

Clemson University researchers recently reported finding a new class of DNA repair-makers.

Chemistry / Biochemistry

created Sep 27, 2011 | popularity 4.3 / 5 (3) | comments 2 | with audio podcast

A question of gene silencing

When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...

Biology / Biotechnology

created Aug 24, 2011 | popularity not rated yet | comments 0

Researchers implicate wayward DNA-repair enzyme in Friedreich's ataxia

Scripps Research Institute scientists have taken a step closer to understanding the cause of Friedreich's ataxia, a debilitating neurological condition that affects tens of thousands of people worldwide, and so far has no ...

Biology / Cell & Microbiology

created Nov 04, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Iniparib extends overall survival in metastatic triple-negative breast cancer

Women with an aggressive subtype of metastatic breast cancer appear to live an average of almost five months longer when treated with iniparib plus chemotherapy, compared to chemotherapy alone, the results of a randomized ...

Medicine & Health / Cancer

created Oct 12, 2010 | popularity not rated yet | comments 0

Researchers advance understanding of enzyme that regulates DNA

Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme.

Biology / Cell & Microbiology

created Aug 20, 2010 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Research Highlights Protein's Role in Cell Health

(PhysOrg.com) -- Simple, but necessary human actions like breathing oxygen can damage our cells' DNA. If left unrepaired, this damage can cause multiple mutations and the type of unregulated cell division common in cancerous ...

Medicine & Health / Medical research

created Jun 09, 2010 | popularity not rated yet | comments 0

Kangaroos may hold skin cancer cure: study

Kangaroos may provide the key to a potential treatment to prevent skin cancer, Australian scientists said Monday.

Medicine & Health / Cancer

created Nov 30, 2009 | popularity not rated yet | comments 0

Scientists uncover function of potential cancer-causing gene product

The Stowers Institute's Conaway Lab has uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. The work was published yesterday by ...

Medicine & Health / Medical research

created Aug 09, 2009 | popularity not rated yet | comments 1

Stopgap DNA repair needs a second step

One can have a dream, two can make that dream so real, goes a popular song. Now a Weizmann Institute study has revealed that it takes two to perform an essential form of DNA repair.

Chemistry / Biochemistry

created May 04, 2009 | popularity 5 / 5 (1) | comments 0

Upside-down world: DNA protecting protein helps cancer drug to kill cells

Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used ...

Biology / Cell & Microbiology

created Apr 28, 2009 | popularity 4.5 / 5 (2) | comments 0

Scientists identify key decision-point at which cells with broken DNA repair themselves or die

When cells undergo potentially catastrophic damage, for example as a result of exposure to ionizing radiation, they must make a decision: either to fix the damage or program themselves for death, a process called apoptosis.

Chemistry / Biochemistry

created Apr 10, 2009 | popularity 5 / 5 (1) | comments 1

DNA repair mechanisms relocate in response to stress

Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found.

Biology / Cell & Microbiology

created Mar 26, 2009 | popularity 5 / 5 (1) | comments 0