Researchers at the A*STAR Institute of Medical Biology (IMB) have discovered a critical checkpoint protein that controls when human embryonic stem cells (hESCs) begin to differentiate.
Cell & Microbiology
Feb 27, 2013
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Over the past several years, Rong Li, Ph.D., at the Stowers Institute for Medical Research has been making crucial discoveries about the development of cell polarity—the process by which one side of a cell becomes different ...
Cell & Microbiology
Jan 22, 2013
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In each cell, thousands of regulatory regions control which genes are active at any time. Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna have developed a method that reliably detects these regions ...
Biotechnology
Jan 18, 2013
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Recently biologists at the University of Massachusetts Amherst led by Wei-lih Lee have identified a new molecular player in asymmetric cell division, a regulatory protein named She1 whose role in chromosome- and spindle positioning ...
Cell & Microbiology
Nov 8, 2012
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(Phys.org)—Abhyudai Singh, assistant professor of electrical and computer engineering at the University of Delaware, describes a new method to understand sources of "noise" in gene-expression that create variability in ...
Biotechnology
Sep 26, 2012
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Bacteria that cause disease in humans have a 'reversible switching mechanism' that allows them to adapt to environments lacking oxygen, scientists at the University of East Anglia (UEA) have found.
Cell & Microbiology
Sep 10, 2012
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(Phys.org)—It's not just a few key genes and proteins that cycle on and off in humans in a 24-hour circadian pattern as the sun rises and falls. Thousands of genes in organs throughout the body show predictable daily fluctuations, ...
Cell & Microbiology
Sep 3, 2012
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For about a dozen years, synthetic biologists have been working on ways to design genetic circuits to perform novel functions such as manufacturing new drugs, producing fuel or even programming the suicide of cancer cells.
Cell & Microbiology
Aug 3, 2012
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In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.
Cell & Microbiology
Jun 7, 2012
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In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Biochemistry
Apr 16, 2012
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