It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...
Evolution
Sep 11, 2018
1
15
The sites where transcription factors bind within regulatory DNA fall into six distinct patterns that overlap with the factors' functions, Broad scientists find, helping advance a goal of regulatory genomics.
Cell & Microbiology
Jul 11, 2018
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7
A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...
Biotechnology
May 4, 2017
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288
A Purdue University study pinpointed an epigenetic mechanism that is a key factor in how genes are switched on and off.
Biotechnology
Oct 13, 2016
1
15
A new study from Michigan State University makes inroads in learning to "read" the genome, a key goal of modern biology.
Biotechnology
May 9, 2016
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37
All the tissues in the human body are made from proteins, and for every protein, there's a stretch of DNA in the human genome that "codes" for it, or describes the sequence of amino acids that will produce it.
Biotechnology
Jan 28, 2016
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81
For graduate student Abe Weintraub, the magic and intrigue of DNA is all in the packaging.
Cell & Microbiology
Oct 27, 2015
0
20
Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie ...
Cell & Microbiology
Apr 16, 2015
0
58
It is easy to distinguish a mouse from a cow. But for members of the same class of mammal, where do such differences begin? In 2011, scientists discovered there were differences in cow and mice blastocysts, the tiny hollow ...
Biotechnology
Feb 23, 2015
2
47
When the mouse and human genomes were catalogued more than 10 years ago, an international team of researchers set out to understand and compare the "mission control centers" found throughout the large stretches of DNA flanking ...
Biotechnology
Nov 19, 2014
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