Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.
Molecular & Computational biology
Feb 28, 2022
0
1748
A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.
Biotechnology
Feb 21, 2022
0
132
Researchers from Hokkaido University have proposed a framework to assist in the demarcation between genetically modified organisms and genome-edited organisms, taking into account both scientific and socio-ethical considerations.
Biotechnology
Jan 24, 2022
0
21
Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory ...
Molecular & Computational biology
Nov 12, 2021
0
304
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
0
30
Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) show signs that they are preserved by natural selection. When G4s are located in the regulatory ...
Molecular & Computational biology
Jun 29, 2021
1
139
Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program," a process that controls when and in what order segments ...
Molecular & Computational biology
Apr 23, 2021
0
1241
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
Biotechnology
Dec 1, 2020
0
29
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice—published this month in Nature Communications—has ...
Biotechnology
May 25, 2020
0
380
Disruption of certain DNA structures—called topologically associating domains, or TADs—is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps ...
Biotechnology
Dec 17, 2019
0
215
